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The use of class A3 and A2L refrigerants to replace conventional hydrofluorocarbons for their low global warming potential (GWP) presents risks due to leaks of flammable mixtures that could result in fire or explosion.

The quality and quantity of refrigerant charge in any vapor compression-based heating and cooling system is vital to its energy efficiency, thermal capacity, and reliability.

The vast majority of energy conversion technologies and industrial processes depend on heat exchangers for transferring heat between fluids.