Available Technologies

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Development of covalent inhibitors of the papain-like protease from SARS-CoV-2

Direct-acting antivirals are needed to combat coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2).

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Stealthy Process Attack Detection for Automated Manufacturing

A team of ORNL scientists led by Brian Sanders has developed a potent and selective covalent inhibitor of the papain-like protease of SARS-CoV-2. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Development of Covalent Inhibitors of the Papain-like Protease from SARS-CoV-2

There is a critical need for new antiviral drugs for treating infections of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2).

ORNL researchers used a laser power bed manufacturing technique to 3D print a lightweight aluminum and cerium-based alloy that can withstand temperatures up to 300 degrees Celsius, proving high strength and durability for automotive, aerospace and defense applications. Credit: ORNL, U.S. Dept. of Energy

Aluminum-Cerium-Nickel Alloys for Additive Manufacturing

A high-strength, heat-resistant Al-Ce-Ni alloy optimized for additive manufacturing in industrial applications.