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- Brian Post
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- Vincent Paquit
- Vlastimil Kunc
- William Alexander
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- Yang Liu
- Yasemin Kaygusuz
- Yukinori Yamamoto

Mechanism-Based Trait Inference in Plants Using Multiplex Networks, AI Agents, and Translation Tools
This system enables the modular design and optimization of complex plant traits by organizing genes and regulatory mechanisms into interpretable clades.

Mechanism-Based Biological Inference via Multiplex Networks, AI Agents and Cross-Species Translation
This invention provides a platform that uses AI agents and biological networks to uncover and interpret disease-relevant biological mechanisms.

Enzymes for synthesis of sequenced oligoamide triads and tetrads that can be polymerized into sequenced copolyamides.
Contact
To learn more about this technology, email partnerships@ornl.gov or call 865-574-1051.

We tested 48 diverse homologs of SfaB and identified several enzyme variants that were more active than SfaB at synthesizing the nylon-6,6 monomer.

We have developed thermophilic bacterial strains that can break down PET and consume ethylene glycol and TPA. This will help enable modern, petroleum-derived plastics to be converted into value-added chemicals.

By engineering the Serine Integrase Assisted Genome Engineering (SAGE) genetic toolkit in an industrial strain of Aspergillus niger, we have established its proof of principle for applicability in Eukaryotes.

US coastal and island communities have vulnerable energy infrastructure and high energy costs, which are exacerbated by climate change.

The invention presented here addresses key challenges associated with counterfeit refrigerants by ensuring safety, maintaining system performance, supporting environmental compliance, and mitigating health and legal risks.

This manufacturing method uses multifunctional materials distributed volumetrically to generate a stiffness-based architecture, where continuous surfaces can be created from flat, rapidly produced geometries.

This invention aims to develop a new feature for a heat pump water heater having a forced flow condenser, coupled with a mixing valve, and a new feature to maximize the first hour rating and provide quick response to hot water demand, comparable to a typical gas water heater.&