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Researcher
- Adam M Guss
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Mechanism-Based Biological Inference via Multiplex Networks, AI Agents and Cross-Species Translation
This invention provides a platform that uses AI agents and biological networks to uncover and interpret disease-relevant biological mechanisms.

By engineering the Serine Integrase Assisted Genome Engineering (SAGE) genetic toolkit in an industrial strain of Aspergillus niger, we have established its proof of principle for applicability in Eukaryotes.

Wind turbine blades face a harsh environment in which erosion of the leading edge is a major factor for in-use maintenance. Current industrial practices to address this leading edge erosion are replacement of reinforcing materials upon significant damage infliction.

Through utilizing a two function splice we can increase the splice strength for opposing tows.
Contact:
To learn more about this technology, email partnerships@ornl.gov or call 865-574-1051.

We proposed and developed a carbon nanofiber (CNF) suspension-based sizing agent, that resulted in improved interfacial, and mechanical properties. The CNF dispersed sizing agent can be applied in a relatively simpler way (by passing the continuous tow through it).

The lack of real-time insights into how materials evolve during laser powder bed fusion has limited the adoption by inhibiting part qualification. The developed approach provides key data needed to fabricate born qualified parts.

We present a comprehensive muti-technique approach for systematic investigation of enzymes generated by wastewater Comamonas species with hitherto unknown functionality to wards the depolymerization of plastics into bioaccessible products for bacterial metabolism.

The technologies polymer cellulose nanocomposite mats and process for making same.
Contact
To learn more about this technology, email partnerships@ornl.gov or call 865-574-1051.

A new nanostructured bainitic steel with accelerated kinetics for bainite formation at 200 C was designed using a coupled CALPHAD, machine learning, and data mining approach.

The use of biomass fiber reinforcement for polymer composite applications, like those in buildings or automotive, has expanded rapidly due to the low cost, high stiffness, and inherent renewability of these materials. Biomass are commonly disposed of as waste.