1 - 10 of 162 Results
Non-covalent inhibitors of SARS-CoV-2 MPro are sought as new antiviral therapies because these compounds are fully reversible non-peptidic inhibitors, they do not interact covalently, and potentially irreversibly, with other proteins in a cell potentially reducing side effects
Plant transformation is a critical but labor-intensive step in validating gene function, creating a major mismatch between gene discovery and experimental validation.
This invention addresses the challenge of weak mechanical strength in hydrogels, which limits their use in biomedical, environmental, and engineering applications.
Plant transformation is widely used for genetic engineering of crop plants. However, the existing plant transformation technology involves multiple manual steps, suffering several limitations such as a high requirement for labor and a low consistence in quality.
We used a novel multiplex network approach to build a mechanistic conceptual model surrounding the regulation of lignin biosynthesis. We found that most genes significantly associated with lignin structures are controlled by networks.
To meet the growing need for cost-effective industrial chemicals, Oak Ridge National Laboratory has developed a method to enable a cellulose-degrading microorganism to produce 2,3-butanediol (2,3-BDO), a valuable precursor for plastics, fuels, and other materials.
Mechanism-Based Trait Inference in Plants Using Multiplex Networks, AI Agents, and Translation Tools
This system enables the modular design and optimization of complex plant traits by organizing genes and regulatory mechanisms into interpretable clades.
Mechanism-Based Biological Inference via Multiplex Networks, AI Agents and Cross-Species Translation
This invention provides a platform that uses AI agents and biological networks to uncover and interpret disease-relevant biological mechanisms.
Ultra-high field MRI provides exceptional resolution but suffers from uneven magnetic field distribution, leading to image artifacts and reduced diagnostic reliability.
We have developed thermophilic bacterial strains that can break down PET and consume ethylene glycol and TPA. This will help enable modern, petroleum-derived plastics to be converted into value-added chemicals.