Genetic modification of microbes that are thermophiles—ones that grow at elevated temperatures—is extremely challenging. Tools developed for E. coli, a typical host for protein production, typically do not function at elevated temperatures.
We have developed an irradiation source plate that can be used to deliver low dose and dose rate radiation to cells (human, animal or microbial) with the limited environment of a 96-well plate.
Cancers driven by KRAS mutations, particularly the KRAS G12C variant, remain difficult to treat and often develop resistance to existing therapies.
AI-Based Platforms for Structural Characterization of Microbial Cells in Low Dose Cryogenic Electron
Gram-negative bacteria continually alter their membrane structure in response to environmental conditions, growth media, and interactions with material surfaces.
This innovative approach combines optical and spectral imaging data via machine learning to accurately predict cancer labels directly from tissue images.
Knowledge graph analytics kernels in High Performance Computing are described
Technologies directed quantum spectroscopy and imaging with Raman and surface-enhanced Raman scattering are described.
We used a novel multiplex network approach to build a mechanistic conceptual model surrounding the regulation of lignin biosynthesis. We found that most genes significantly associated with lignin structures are controlled by networks.