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Different groups of proteins shown in different colors combine and attach to a broken strand of DNA.

Researchers at Georgia State University used the Summit supercomputer to study an elaborate molecular pathway called nucleotide excision repair. Decoding NER’s sophisticated sequence of events and the role of PInC in the pathway could provide key insights into developing novel treatments and preventing conditions that lead to premature aging and certain types of cancer.

Secretary Wright leans over red computer door, signing with silver sharpie as ORNL Director Stephen Streiffer looks on

During his first visit to Oak Ridge National Laboratory, Energy Secretary Chris Wright compared the urgency of the Lab’s World War II beginnings to today’s global race to lead in artificial intelligence, calling for a “Manhattan Project 2.”

Six images fanned out across the right side of the page with the first page showcasing the report cover. To the right hand side is a green oak leaf.

A workshop led by scientists at ORNL sketched a road map toward a longtime goal: development of autonomous, or self-driving, next-generation research laboratories. 

Picture shows magnetic domains in uranium with a blue and orange organic shapes, similar to lava flowing through water, but in graphic form

The US focuses on nuclear nonproliferation, and ORNL plays a key role in this mission. The lab conducts advanced research in uranium science, materials analysis and nuclear forensics to detect illicit nuclear activities. Using cutting-edge tools and operational systems, ORNL supports global efforts to reduce nuclear threats by uncovering the history of nuclear materials and providing solutions for uranium removal. 

ORNL computing staff members Hector Suarez (middle) and William Castillo (right) talk HPC at the Tapia Conference career fair in San Diego, California. Credit: ORNL, U.S. Dept of Energy

The National Center for Computational Sciences, located at the Department of Energy’s Oak Ridge National Laboratory, made a strong showing at computing conferences this fall. Staff from across the center participated in numerous workshops and invited speaking engagements.

A small sample from the Frontier simulations reveals the evolution of the expanding universe in a region containing a massive cluster of galaxies from billions of years ago to present day (left).

In early November, researchers at the Department of Energy’s Argonne National Laboratory used the fastest supercomputer on the planet to run the largest astrophysical simulation of the universe ever conducted. The achievement was made using the Frontier supercomputer at Oak Ridge National Laboratory. 

7 people from ORBIT research team accept their award from Tom Tabor (middle)

ORNL has been recognized in the 21st edition of the HPCwire Readers’ and Editors’ Choice Awards, presented at the 2024 International Conference for High Performance Computing, Networking, Storage and Analysis in Atlanta, Georgia.

Black computing cabinets in a row on a white floor in the data center that houses the Frontier supercomputer at Oak Ridge National Laboratory

Two-and-a-half years after breaking the exascale barrier, the Frontier supercomputer at the Department of Energy’s Oak Ridge National Laboratory continues to set new standards for its computing speed and performance.

Graphic representation of ai model that identifies proteins

Researchers used the world’s fastest supercomputer, Frontier, to train an AI model that designs proteins, with applications in fields like vaccines, cancer treatments, and environmental bioremediation. The study earned a finalist nomination for the Gordon Bell Prize, recognizing innovation in high-performance computing for science.

Pictured here are 9 scientists standing in a line in front of the frontier supercomputer logo/computer

Researchers at Oak Ridge National Laboratory used the Frontier supercomputer to train the world’s largest AI model for weather prediction, paving the way for hyperlocal, ultra-accurate forecasts. This achievement earned them a finalist nomination for the prestigious Gordon Bell Prize for Climate Modeling.