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From decoding plant genomes to modeling microbial behavior, computational biologist Priya Ranjan builds computational tools that turn extensive biological datasets into real-world insights. These tools transform the way scientists ask and answer complex biological questions that advance biotechnology breakthroughs and support cultivation of better crops for energy and food security.

Analyzing massive datasets from nuclear physics experiments can take hours or days to process, but researchers are working to radically reduce that time to mere seconds using special software being developed at the Department of Energy’s Lawrence Berkeley and Oak Ridge national laboratories.

Scientists at ORNL have developed a vacuum-assisted extrusion method that reduces internal porosity by up to 75% in large-scale 3D-printed polymer parts. This new technique addresses the critical issue of porosity in large-scale prints but also paves the way for stronger composites.
Researchers at Oak Ridge National Laboratory have developed a modeling method that uses machine learning to accurately simulate electric grid behavior while protecting proprietary equipment details. The approach overcomes a key barrier to accurate grid modeling, helping utilities plan for future demand and prevent blackouts.
Robert “Bob” Hettich, an ORNL Corporate Fellow, is a pioneer in using mass spectrometry to uncover how microbes interact within complex environments and influence larger systems like plants and humans. A founder of the field of metaproteomics, he leads research that supports bioenergy, environmental resilience and health through advanced protein analysis.
Daniel Jacobson, distinguished research scientist in the Biosciences Division at ORNL, has been elected a Fellow of the American Institute for Medical and Biological Engineering, or AIMBE, for his achievements in computational biology.

A team from ORNL, joined by university students, recently traveled to the Ohio State University Research Reactor to conduct a novel experiment on nuclear thermal rocket fuel coatings — one that could help propel NASA’s astronauts to Mars faster and more efficiently.
Dave Weston studies how microorganisms influence plant health and stress tolerance, using the Advanced Plant Phenotyping Laboratory to accelerate research on plant-microbe interactions and develop resilient crops for advanced fuels, chemicals and
Scientists at ORNL have developed a method that can track chemical changes in molten salt in real time — helping to pave the way for the deployment of molten salt reactors for energy production.

During his first visit to Oak Ridge National Laboratory, Energy Secretary Chris Wright compared the urgency of the Lab’s World War II beginnings to today’s global race to lead in artificial intelligence, calling for a “Manhattan Project 2.”