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From decoding plant genomes to modeling microbial behavior, computational biologist Priya Ranjan builds computational tools that turn extensive biological datasets into real-world insights. These tools transform the way scientists ask and answer complex biological questions that advance biotechnology breakthroughs and support cultivation of better crops for energy and food security.

Scientists have developed a new machine learning approach that accurately predicted critical and difficult-to-compute properties of molten salts, materials with diverse nuclear energy applications.

Jesse Labbé aims to leverage biology, computation and engineering to address societal challenges related to energy, national security and health, while enhancing U.S. competitiveness. Labbé emphasizes the importance of translating groundbreaking research into practical applications that have real-world impact.

Scientists at Oak Ridge National Laboratory and the University of Colorado Boulder used a gene-silencing tool and a large library of molecular guides to understand how photosynthetic bacteria adapt to light and temperature changes. They found that even partial suppression of certain genes yielded big benefits in modifying the stress response of wild microbes.
Robert “Bob” Hettich, an ORNL Corporate Fellow, is a pioneer in using mass spectrometry to uncover how microbes interact within complex environments and influence larger systems like plants and humans. A founder of the field of metaproteomics, he leads research that supports bioenergy, environmental resilience and health through advanced protein analysis.
Dave Weston studies how microorganisms influence plant health and stress tolerance, using the Advanced Plant Phenotyping Laboratory to accelerate research on plant-microbe interactions and develop resilient crops for advanced fuels, chemicals and

Hugh O’Neill’s lifelong fascination with the complexities of the natural world drives his research at ORNL, where he’s using powerful neutron beams to dive deep into the microscopic realm of biological materials and unlock secrets for better production of domestic biofuels and bioproducts.

Phong Le is a computational hydrologist at ORNL who is putting his skills in hydrology, numerical modeling, machine learning and high-performance computing to work quantifying water-related risks for humans and the environment.

Researchers at Stanford University, the European Center for Medium-Range Weather Forecasts, or ECMWF, and ORNL used the lab’s Summit supercomputer to better understand atmospheric gravity waves, which influence significant weather patterns that are difficult to forecast.

Scientists at ORNL are studying the failure mechanisms of a new solid electrolyte battery to enhance long-term storage for renewable energy, aiming to make wind and solar power more reliable for the electric grid.