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ORNL researcher Priya Ranjan standing outside in front of brick pillars

From decoding plant genomes to modeling microbial behavior, computational biologist Priya Ranjan builds computational tools that turn extensive biological datasets into real-world insights. These tools transform the way scientists ask and answer complex biological questions that advance biotechnology breakthroughs and support cultivation of better crops for energy and food security. 

Three profile photos of ORNL researchers are cut out into one image representing three new members of leadership for the Center for Bioenergy Innovation

The Center for Bioenergy Innovation, or CBI, at the Department of Energy’s Oak Ridge National Laboratory has promoted Melissa Cregger and Carrie Eckert to serve as chief science officers, advancing the center’s mission of innovations for new domestic biofuels, chemicals and materials.

ORNL researcher Van Graves examines a transparent cylindrical device he developed and tested at CERN in 2007 to demonstrate that a jet of liquid mercury could serve as a target for a neutrino factory or muon collider.

Van Graves, an engineering manager at ORNL, is celebrating 40 years of dedicated service leading a diverse range of prominent engineering projects at ORNL and internationally. 

Five scientists and one in a boat are conducting fish sampling for the biological monitoring program on the DOE Oak Ridge Reservation.

ORNL’s Biological Monitoring and Abatement Program, or BMAP, is marking 40 years of helping steward the DOE’s 33,476 acres of land on which some of the nation’s most powerful science and technology missions are carried out. 

Graphic depiction of a neutron star, which looks like orange beans inside a cage

Using the Frontier supercomputer, a team of researchers from the Massachusetts Institute of Technology conducted large-scale calculations to chart the isospin density of a neutron star across a range of conditions. Their work provides new insights into how pressure and density interact within neutron stars, offering important predictions about their inner workings.

A 3D printing nozzle wrapped in insulation extrudes black composite material into a small square mold on a green and white flat surface in a lab setting. Inset shows a close-up of a pressure gauge connected to brass valves and tubing.

Scientists at ORNL have developed a vacuum-assisted extrusion method that reduces internal porosity by up to 75% in large-scale 3D-printed polymer parts. This new technique addresses the critical issue of porosity in large-scale prints but also paves the way for stronger composites. 

ORNL researcher Jesse Labbe is working with plants in a greenhouse. He is framed on all sides with bright green leaves

Jesse Labbé aims to leverage biology, computation and engineering to address societal challenges related to energy, national security and health, while enhancing U.S. competitiveness. Labbé emphasizes the importance of translating groundbreaking research into practical applications that have real-world impact.

Illustration of a glowing black box emitting digital particles that form into a 3D model of an electrical grid infrastructure, set against a background of binary code and data visualizations.

Researchers at Oak Ridge National Laboratory have developed a modeling method that uses machine learning to accurately simulate electric grid behavior while protecting proprietary equipment details. The approach overcomes a key barrier to accurate grid modeling, helping utilities plan for future demand and prevent blackouts. 

 

A 3D rendering of a large, white protein complex bound to a purple strand of guide RNA, which is aligned with a blue double-helix DNA strand. The background is a soft gray with scattered, blurred molecular shapes.

Scientists at Oak Ridge National Laboratory and the University of Colorado Boulder used a gene-silencing tool and a large library of molecular guides to understand how photosynthetic bacteria adapt to light and temperature changes. They found that even partial suppression of certain genes yielded big benefits in modifying the stress response of wild microbes. 

A three-leaf plant microbe on a grid slide with three gold circles to the bottom left

ORNL scientists are using synthetic communities to simplify underground ecosystems to better understand the interactions between plants and microbes, informing the development of better bioenergy crops for domestic energy production.