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Scientists at the Department of Energy’s Oak Ridge National Laboratory recently welcomed Vanderbilt University colleagues for a symposium on basic science research, with a focus on potential collaborations in the biomedical and biotechnology spaces.

Daniel Jacobson, distinguished research scientist in the Biosciences Division at ORNL, has been elected a Fellow of the American Institute for Medical and Biological Engineering, or AIMBE, for his achievements in computational biology. 

Scientists at ORNL have developed a method that can track chemical changes in molten salt in real time — helping to pave the way for the deployment of molten salt reactors for energy production.

Researchers at Georgia State University used the Summit supercomputer to study an elaborate molecular pathway called nucleotide excision repair. Decoding NER’s sophisticated sequence of events and the role of PInC in the pathway could provide key insights into developing novel treatments and preventing conditions that lead to premature aging and certain types of cancer.

During his first visit to Oak Ridge National Laboratory, Energy Secretary Chris Wright compared the urgency of the Lab’s World War II beginnings to today’s global race to lead in artificial intelligence, calling for a “Manhattan Project 2.”

Scientists designing the world’s first controlled nuclear fusion power plant, ITER, needed to solve the problem of runaway electrons, negatively charged particles in the soup of matter in the plasma within the tokamak, the magnetic bottle intended to contain the massive energy produced. Simulations performed on Summit, the 200-petaflop supercomputer at ORNL, could offer the first step toward a solution.

Ryan Culler is the program manager at Oak Ridge National Laboratory, where he oversees the production of actinium-225, a promising treatment for cancer. Driven by a personal connection to cancer through his late brother, Culler is dedicated to advancing medical isotopes to help improve cancer care. 

Scientists conducted a groundbreaking study on the genetic data of over half a million U.S. veterans, using tools from the Oak Ridge National Laboratory to analyze 2,068 traits from the Million Veteran Program.

The US focuses on nuclear nonproliferation, and ORNL plays a key role in this mission. The lab conducts advanced research in uranium science, materials analysis and nuclear forensics to detect illicit nuclear activities. Using cutting-edge tools and operational systems, ORNL supports global efforts to reduce nuclear threats by uncovering the history of nuclear materials and providing solutions for uranium removal. 

Researchers used the world’s fastest supercomputer, Frontier, to train an AI model that designs proteins, with applications in fields like vaccines, cancer treatments, and environmental bioremediation. The study earned a finalist nomination for the Gordon Bell Prize, recognizing innovation in high-performance computing for science.