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Mass Spectrometry and Laser Spectroscopy


The Mass Spectrometry and Laser Spectroscopy group is a diverse team of experts in analytical and physical chemistry with an extensive range of state-of-the-art and novel instrumentation used for fundamental and applied research based around mass spectrometry and laser spectroscopy of complex systems.

Much of our current research focuses on:

  1. Multimodal imaging for chemical imaging of plant-microbial interactions, interfaces, tissues and other complex systems
  2. Nonlinear laser spectroscopy and microscopy of electronic and molecular processes in complex materials
  3. Mass spectrometry for high throughput and sensitive chemical characterization

We specialize in developing the next generation of technologies to probe and chemically characterize complex systems.



We Are Hiring!

We are seeking a Postdoctoral Research Associate who will focus on developing a new multimodal imaging platform integrating novel and existing optical and mass spectroscopy capabilities. Apply Here


Instrument Capabilities

Mass Spectrometry

High Resolution Orbitrap MS

High Resolution Time-of-Flight MS

Triple Quadrupole MS

Ion Mobility Time-of-Flight


Ultrafast and Surface Specific Spectroscopy

Vibrational Sum Frequency Generation

Electronic Sum Frequency Generation

Transient Absorption Spectroscopy

Liquid Extraction-Surface Sampling

Open-Port Sampling Interface



Liquid-Vortex Capture

Nonlinear Optical Imaging

Transient Absorption Microscopy

Coherent anti-Stokes Raman Microscopy

Sum Frequency and Second Harmonic Generation Microscopy

Multiphoton Fluorescence Microscopy

Our Group in the News

ORNL video highlights MSLS single cell analysis technology

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Ben Doughty Wins DOE BES Early Career Award

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Open Port Sampling Interface Wins Technology Transfer Award

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MSLS Group Wins Federal Laboratory Consortium award for OPSI Invention

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TouchExpress OPSI Featured in The Analytical Scientist

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Advion Introduces TouchExpress Open Port Sampling Interface for their expression® Compact Mass Spectrometer (CMS)

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Open Port Sampling Interface (OPSI) Licensed

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