Paul E Abraham

Bioanalytical Chemist

Dr. Paul E. Abraham is a Bioanalytical Chemist in the Biosciences Division at Oak Ridge National Laboratory. He has over 10 years of experience in biological mass spectrometry, with a particular focus on the development and application of new innovative, high-throughput, mass spectrometry-based approaches to achieve systems-level understanding of plants, microbes, and microbial communities. His research plays a key role in interdisciplinary approaches to integrate large-scale systems biology (i.e., genomics, epigenomics, transcriptomics, proteomics, metabolomics, and other “-omics”) with computational biology and systems-scale modeling of biological networks to comprehensively understand the fundamental principles driving biological systems under changing conditions. Dr. Abraham’s major research focus is to fill these knowledge gaps to enable the design and engineering of plants and microbes to confer new functionalities for defined purposes and, in turn, learn from re-engineered organisms.

Dr. Abraham is the Laboratory Research Manager for the Secure Ecosystem Engineering and Design (SEED) project ( that is funded by the Genomic Science Program of the U.S. Department of Energy, Office of Science, Office of Biological and Environmental Research (BER) as part of the Secure Biosystems Design Science Focus Area (SFA).