Paul E Abraham

Paul E Abraham

Bioanalytical Chemist


Dr. Paul E. Abraham is a Bioanalytical Chemist in the Chemical Sciences Division at Oak Ridge National Laboratory. He has over 10 years of experience in biological mass spectrometry, with a particular focus on the development and application of new innovative, high-throughput, mass spectrometry-based approaches to achieve systems-level understanding of plants, microbes, and microbial communities. His research plays a key role in interdisciplinary approaches to integrate large-scale systems biology (i.e., genomics, epigenomics, transcriptomics, proteomics, metabolomics, and other “-omics”) with computational biology and systems-scale modeling of biological networks to comprehensively understand the fundamental principles driving biological systems under changing conditions. Dr. Abraham’s major research focus is to achieve this knowledge to enable the design and engineering of plants and microbes to confer new functionalities for defined purposes and, in turn, learn from re-engineered organisms.


Exploring the genetic mechanisms of crassulacean acid metabolism (CAM) and drought tolerance in desert-adapted plants (