Leighton Coates STS Instrument Systems Manager Contact coatesl@ornl.gov | 865.574.4620 All Publications Second Target Station Project: STS/PSD/ESTD Workshop on Batteries and Energy Storage Insights into the mechanism of SARS-CoV-2 main protease autocatalytic maturation from model precursors Contribution of the catalytic dyad of SARS-CoV-2 main protease to binding covalent and noncovalent inhibitors AI-Accelerated Design of Targeted Covalent Inhibitors for SARS-CoV-2... A realistic guide misalignment model for the Second Target Station instruments at the Spallation Neutron Source ORNL Second Target Station Project: Biological & Environmental Science Workshop... Unmasking the Conformational Stability and Inhibitor Binding to SARS-CoV-2 Main Protease Active Site Mutants and Miniprecurso... Autoprocessing and oxyanion loop reorganization upon GC373 and nirmatrelvir binding of monomeric SARS-CoV-2 main protease cat... Cryo neutron crystallography demonstrates influence of RNA 2′-OH orientation on conformation, sugar pucker and water struct... EWALD: A Macromolecular Diffractometer for the Second Target Station... The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room... Hit Expansion of a Noncovalent SARS-CoV-2 Main Protease Inhibitor... Covalent narlaprevir- and boceprevir-derived hybrid inhibitors of SARS-CoV-2 main protease... Detector needs for STS instruments... Cryotrapping peroxide in the active site of human mitochondrial manganese superoxide dismutase crystals for neutron diffracti... High-Throughput Virtual Screening and Validation of a SARS-CoV-2 Main Protease Noncovalent Inhibitor... Structural, Electronic, and Electrostatic Determinants for Inhibitor Binding to Subsites S1 and S2 in SARS-CoV-2 Main Proteas... Michaelis-like complex of SARS-CoV-2 main protease visualized by room-temperature X-ray crystallography... Toho-1 β-lactamase: backbone chemical shift assignments and changes in dynamics upon binding with avibactam... Second Target Station Instrument Systems Research and Development Plan... Structural plasticity of the selectivity filter in a nonselective ion channel... Water structure around a left-handed Z-DNA fragment analyzed by cryo neutron crystallography... Direct detection of coupled proton and electron transfers in human manganese superoxide dismutase... Direct Observation of Protonation State Modulation in SARS-CoV-2 Main Protease upon Inhibitor Binding with Neutron Crystallog... Probing the SARS-CoV-2 main protease active site as a target to inhibit viral replication... Pagination Current page 1 Page 2 Page 3 Next page ›› Last page Last » Key Links Google Scholar ORCID Second Target Station Pittsburgh Diffraction Society Google Scholar
