(a), (b) Designed structures of cone and sphere; (c), (d) 3D-printed cone and sphere; (e), (f) Pyrolyzed carbon cone and sphere
Scientific Achievement
Size and geometry customizable carbon microelectrode sensors were successfully fabricated and implanted into a rat brain to detect dopamine release in vivo.
Significance and Impact
The novel method allows batch-fabrication of size and geometry customizable microsensors as implantable neurochemical devices.
Research Details
- Microstructures were 3D-printed by direct laser writing, and carbonized by rapid thermal processing.
- Surface and electrochemical characterizations proved high reproducibility and electroactive surface of the printed electrodes.
- 3D-printed electrodes were implanted into a rat brain and enable monitoring dopamine release in vivo.
C. Yang, Q. Cao, P. Puthongkham, S. T. Lee, M. Ganesana, N. V. Lavrik, and B. J. Venton, "3D-printed carbon electrodes for neurotransmitter detection," Angew.Chem. Int. Ed. 57, 14255–14259 (2018). DOI: 10.1002/anie.201809992
