Kevin L Weiss Senior Technical Staff Contact weisskl@ornl.gov | 865.805.7388 All Publications Unusual zwitterionic catalytic site of SARS–CoV-2 main protease revealed by neutron crystallography... Substrate Binding Stiffens Aspartate Aminotransferase by Altering the Enzyme Picosecond Vibrational Dynamics... A nucleotide-dependent oligomerization of the Escherichia coli replication initiator DnaA requires residue His136 for remodel... Pressure and Temperature Effects on the Formation of Aminoacrylate Intermediates of Tyrosine Phenol-lyase Demonstrate Reactio... Zooming in on protons: Neutron structure of protein kinase A trapped in a product complex... Substrate Binding Induces Conformational Changes in a Class A β-lactamase That Prime It for Catalysis... "To Be or Not to Be" Protonated: Atomic Details of Human Carbonic Anhydrase-Clinical Drug Complexes by Neutron Crystallograph... Solution Structure of an Intramembrane Aspartyl Protease via Small Angle Neutron Scattering... Direct visualization of critical hydrogen atoms in a pyridoxal 5′-phosphate enzyme... Preliminary neutron diffraction analysis of challenging human manganese superoxide dismutase crystals... Long‐Range Electrostatics‐Induced Two‐Proton Transfer Captured by Neutron Crystallography in an Enzyme Catalytic Site... The Bio-SANS instrument at the High Flux Isotope Reactor of Oak Ridge National Laboratory... X-ray Crystallographic Studies of Family 11 Xylanase Michaelis and Product Complexes: Implications for the Catalytic Mechani... Heterologous expression, purification, crystallization and preliminary X-ray analysis of Trichoderma reesei Xylanase II and f... Domain crossover in the reductase subunit of NADPH-dependent assimilatory sulfite reductase Structural characterization of an intrinsically disordered protein complex using integrated small-angle neutron scattering an... Revealing protonation states and tracking substrate in serine hydroxymethyltransferase with room-temperature X-ray and neutron crystallography SCOMAP-XD: atomistic deuterium contrast matching for small-angle neutron scattering in biology... Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2... An N⋯H⋯N low-barrier hydrogen bond preorganizes the catalytic site of aspartate aminotransferase to facilitate the second... Neutron scattering maps the higher-order assembly of NADPH-dependent assimilatory sulfite reductase... Covalent narlaprevir- and boceprevir-derived hybrid inhibitors of SARS-CoV-2 main protease... Cryotrapping peroxide in the active site of human mitochondrial manganese superoxide dismutase crystals for neutron diffracti... Structural, Electronic, and Electrostatic Determinants for Inhibitor Binding to Subsites S1 and S2 in SARS-CoV-2 Main Proteas... Fed-batch production of deuterated protein in Escherichia coli for neutron scattering experimentation... Pagination Current page 1 Page 2 Page 3 Next page ›› Last page Last » Key Links ORCID Organizations Neutron Sciences Directorate Neutron Scattering Division Large Scale Structures Section Biological Labeling and Scattering Group User Facilities Center for Structural Molecular Biology High Flux Isotope Reactor Spallation Neutron Source
