Hugh M O'Neill Group Leader, Biological Labeling and Scattering Contact oneillhm@ornl.gov | 865.574.5283 All Publications SCOMAP-XD: atomistic deuterium contrast matching for small-angle neutron scattering in biology Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2... Spatially confined protein assembly in hierarchical mesoporous metal-organic framework Amphiphilic Co-Solvents Modulate the Structure of Membrane Domains... ORNL Second Target Station Project: Biological & Environmental Science Workshop... Assessment of antimicrobial activity of melittin encapsulated in bicontinuous microemulsions prepared using renewable oils Modeling the partitioning of amphiphilic molecules and co-solvents in biomembranes... Small angle neutron scattering and lipidomic analysis of a native, trimeric PSI-SMALP from a thermophilic cyanobacteria... Experimental mapping of short-wavelength phonons in proteins... Structural Reorganization of Noncellulosic Polymers Observed In Situ during Dilute Acid Pretreatment by Small-Angle Neutron S... New Technologies are Needed to Improve the Recycling and Upcycling of Waste Plastics... Fed-batch production of deuterated protein in Escherichia coli for neutron scattering experimentation... Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication... Small Angle Neutron Scattering Shows Nanoscale PMMA Distribution in Transparent Wood Biocomposites... Unusual zwitterionic catalytic site of SARS–CoV-2 main protease revealed by neutron crystallography... Malleability of the SARS-CoV-2 3CL Mpro Active-Site Cavity Facilitates Binding of Clinical Antivirals... Model-based Reconstruction for Single Particle Cryo-Electron Microscopy... Room-temperature X-ray crystallography reveals the oxidation and reactivity of cysteine residues in SARS-CoV-2 3CL Mpro: insi... Structural Insights into Low and High Recalcitrance Natural Poplar Variants Using Neutron and X-ray Scattering... Deconstruction of biomass enabled by local demixing of cosolvents at cellulose and lignin surfaces... Deconstruction of biomass enabled by local demixing of cosolvents at cellulose and lignin surfaces... Effects of soil particles and convective transport on dispersion and aggregation of nanoplastics via small-angle neutron scat... Structural plasticity of SARS-CoV-2 3CL Mpro active site cavity revealed by room temperature X-ray crystallography... Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer... Ammonia-salt solvent promotes cellulosic biomass deconstruction under ambient pretreatment conditions to enable rapid soluble... Pagination Current page 1 Page 2 Page 3 … Next page ›› Last page Last » Key Links Curriculum Vitae ORCID Organizations Neutron Sciences Directorate User Facilities Center for Structural Molecular Biology