April 2013

Journal

Solvent effects on proteinfast dynamics: iplications for biopreservation

By:
Garcia Sakai, V; Khodadadi, S; Cicerone, Marcus; Curtis, J. E.; Sokolov, Alexei P; Roh, J
Journal Name:
Soft Matter
Page Number:
5336-5340
Volume:
9
Issue Number:
22
Publication Date:
April 2013
View DOI Listing:
https://doi.org/10.1039/c3sm50492a

Abstract

In the context of biopreservation, we study the influence of water, glycerol and trehalose on the ps–ns dynamics of lyzosyme using neutron scattering. Results indicate that the choice of bioprotectant depends on the storage temperature; glycerol is the most effective for low temperatures and trehalose for high temperatures.


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