August 2012

Journal

A flow cytometry-based dopamine transporter binding assay using antagonist-conjugated quantum dots

By:
Kovtun, Oleg; Ross, Emily; Tomlinson, Ian; Rosenthal, Sandra J
Journal Name:
Chemical Communications
Page Number:
5426-5430
Volume:
48
Issue Number:
44
Publication Date:
August 2012
View DOI Listing:
https://doi.org/10.1039/c2cc31951a

Abstract

Here we present the development and validation of a flow cytometry-based dopamine transporter (DAT) binding assay that uses antagonist-conjugated quantum dots (QDs).We anticipate that our QD-based assay is of immediate value to the high throughput screening of novel DAT modulators.