Research in the Systems Genetics group is supported by large U.S. Department of Energy Biological and Environmental Research (BER) programs including the Bioenergy Science Center, the Plant-Microbe Interface SFA, CSiTE, as well as by individual investigator-driven projects from DOE and other federal agencies (NIH, NASA, NSF). Subject areas include biofuels and microbial engineering; the roles of microbes in plant development, in regional and global elemental cycles related to bioremediation and climate changes; the human microbiome and its role in health and disease; integrating genomic and microbiological approaches to study novel lineages of Archaea and Bacteria.
Insights into the Evolution of Host Association through the Isolation and Characterization of a Novel Human Periodontal Pathobiont, Desulfobulbus oralis
Capabilities & Research Areas
As part of these research areas, we study organisms (archaea, bacteria, fungi) from a wide range of environments, including terrestrial geothermal and marine hydrothermal systems, soils and plant rhizospheres, subsurface aquifers and forests and bogs. A wide range of approaches are being used, from traditional cultivation and physiology studies to community diversity characterization, metagenomics and single-cell genomics, integrated “omics” (transcriptomics-proteomics-metabolomics), and advanced cellular isolation and imaging.