Microbial Ecology and Physiology

Microbial Ecology and Physiology

The Microbial Ecology and Physiology Group focuses on microbial ecology and genomics of environmental organisms. The research is concerned with the basic science underlying bioenergy production, bioremediation efforts, carbon cycling and sequestration, as well as other uses of biotechnology.

Microbial Ecology and Physiology


Insights into the Evolution of Host Association through the Isolation and Characterization of a Novel Human Periodontal Pathobiont, Desulfobulbus oralis

The human oral microbiota encompasses representatives of many bacterial lineages that have not yet been cultured. Here we describe the isolation and characterization of previously uncultured...

Development of a high efficiency integration system and promoter library for rapid modification of Pseudomonas putida KT2440

Pseudomonas putida strains are highly robust bacteria known for their ability to efficiently utilize a variety of carbon sources, including aliphatic and aromatic hydrocarbons. Recently, P. putida...

One-Pot Process in Scalable Bath for Water-Dispersed ZnS Nanocrystals with the Tailored Size

Well-dispersed ZnS nanocrystals with tailored size in aqueous solutions were synthesized by employing cysteine-sulfur (Cys-S) complexes with low molecular weight in a scalable anoxic vessel.High...

Capabilities & Research Areas

The research couples molecular biology, DNA technology, genomics, and bioreporter techniques with traditional microbiological methods to investigate microbial communities and the processes by which microorganisms transform materials and energy. The goal of these investigations is to increase the understanding of bioenergy production, microbial ecology, nutrient cycling, carbon sequestration, and microbial degradation of hazardous contaminants; to demonstrate application of innovative microbial techniques and bioremediation approaches in solving the U.S. Department of Energy's (DOE) and the nation's sediment, soil, surface water, and ground water contamination problems; and to transfer new technology to industry. Much of the funding for the group is provided by the DOE Office of Biological and Environmental Research (BER), and by the DOE Office of Fossil Energy. The group participates in the research conducted at ORNL by the Bioenergy Science Center (BESC).


David E Graham

Microbial Ecology & Physiology Group Leader