Computational Biology and Bioinformatics

Computational Biology and Bioinformatics

The ORNL Computational Biology Program consists of members of Biosciences Division, Computer Science and Mathematics Division, and Environmental Sciences Division. It is oriented toward various aspects of genome and proteome analysis, and molecular systems biology.

Computational Biology and Bioinformatics


The Sphagnome Project: enabling ecological and evolutionary insights through a genus-level sequencing project

Considerable progress has been made in ecological and evolutionary genetics with studies demonstrating how genes underlying plant and microbial traits can influence adaptation and even ‘extend’ to...

Complete Genome Sequence of Alkaliphilus metalliredigens QYMF, an Alkaliphilic and Metal-Reducing Bacterium Isolated from Borax-contaminated Leachate Ponds

Alkaliphilus metalliredigens strain QYMF is an anaerobic, alkaliphilic, and metal-reducing bacterium associated with phylum Firmicutes. QYMF was isolated from alkaline borax leachate ponds. The...

Capabilities & Research Areas

Elements of the effort include: Genome Analysis and Annotation; Databases, Data Integration and Collaboratory Systems; Molecular Modeling and Simulation; Mass Spectrometry Analysis; Metabolic and Regulatory Modeling; High Performance Biocomputing; Computational Biology Graduate Training; and Center for Molecular Biophysics.



Robert W Cottingham

Group Leader, Computational Biology and Bioinformatics