BAC End Sequencing Extends Contigs.  Software tools are helping to position STCs. One tool, provided by the Genome Channel, allows investigators to view the contig positions of more than 15,000 BAC end sequences and their relationships to other clones and predicted genes and exons (gene-coding regions). In the figure, the black bar represents 250kb of a much longer contig. Below the bar, the long horizontal lines denote BAC clones, of which the first, fifth, and sixth are candidates for extending the seed contig to the left. Above the bar, vertical tick marks indicate exons as predicted by GRAIL software.  Exons connected by short horizontal lines represent putative gene models for the contig's forward DNA strand.
 

The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v10n1-2)