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Genetic analysis revealed connections between inflammatory activity and development of atomic dermatitis, according to researchers from the UPenn School of Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory. Credit: Kang Ko/UPenn

University of Pennsylvania researchers called on computational systems biology expertise at Oak Ridge National Laboratory to analyze large datasets of single-cell RNA sequencing from skin samples afflicted with atopic dermatitis.

Deborah Frincke, one of the nation’s preeminent computer scientists and cybersecurity experts, serves as associate laboratory director of ORNL’s National Security Science Directorate. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Deborah Frincke, one of the nation’s preeminent computer scientists and cybersecurity experts, serves as associate laboratory director of ORNL’s National Security Science Directorate. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

ORNL assisted in investigating proteins called porins, one shown in red, which are found in the protective outer membrane of certain disease-causing bacteria and tether the membrane to the cell wall. Credit: Hyea (Sunny) Hwang/Georgia Tech and ORNL, U.S. Dept. of Energy

Scientists from Oak Ridge National Laboratory used high-performance computing to create protein models that helped reveal how the outer membrane is tethered to the cell membrane in certain bacteria.

Simulation of short polymer chains

Oak Ridge National Laboratory scientists have discovered a cost-effective way to significantly improve the mechanical performance of common polymer nanocomposite materials.

Computing – Mining for COVID-19 connections

Scientists have tapped the immense power of the Summit supercomputer at Oak Ridge National Laboratory to comb through millions of medical journal articles to identify potential vaccines, drugs and effective measures that could suppress or stop the

A new computational approach by ORNL can more quickly scan large-scale satellite images, such as these of Puerto Rico, for more accurate mapping of complex infrastructure like buildings. Credit: Maxar Technologies and Dalton Lunga/Oak Ridge National Laboratory, U.S. Dept. of Energy

A novel approach developed by scientists at ORNL can scan massive datasets of large-scale satellite images to more accurately map infrastructure – such as buildings and roads – in hours versus days. 

ORNL’s collaboration with Cincinati Children’s Hospital Medical Center will leverage the lab’s expertise in high-performance computing and safe, secure recordkeeping. Credit: Genevieve Martin/Oak Ridge National Laboratory, U.S. Dept. of Energy

Oak Ridge National Laboratory will partner with Cincinnati Children’s Hospital Medical Center to explore ways to deploy expertise in health data science that could more quickly identify patients’ mental health risk factors and aid in

This simulation of a fusion plasma calculation result shows the interaction of two counter-streaming beams of super-heated gas. Credit: David L. Green/Oak Ridge National Laboratory, U.S. Dept. of Energy

The prospect of simulating a fusion plasma is a step closer to reality thanks to a new computational tool developed by scientists in fusion physics, computer science and mathematics at ORNL.

Dalton Lunga

A typhoon strikes an island in the Pacific Ocean, downing power lines and cell towers. An earthquake hits a remote mountainous region, destroying structures and leaving no communication infrastructure behind.

Project bridges compute staff, resources at ORNL and VA health data to speed suicide risk screening for US veterans. Image Credit: Carlos Jones, ORNL

In collaboration with the Department of Veterans Affairs, a team at Oak Ridge National Laboratory has expanded a VA-developed predictive computing model to identify veterans at risk of suicide and sped it up to run 300 times faster, a gain that could profoundly affect the VA’s ability to reach susceptible veterans quickly.