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ORNL researchers led by Michael Garvin, left, and David Kainer discovered genetic mutations called structural variants and linked them to autism spectrum disorders, demonstrating an approach that could be used to develop better diagnostics and drug therapies. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

ORNL researchers discovered genetic mutations that underlie autism using a new approach that could lead to better diagnostics and drug therapies.

Researchers from ORNL and Argonne National Laboratory will work with Wabtec, a leading manufacturer of freight locomotives, to develop the hardware and control strategies for a single cylinder, dual-fuel engine to demonstrate the viability of using alternative fuels for locomotives. The team’s goal is to reduce carbon emissions from the roughly 25,000 locomotives already in use in North America. Credit: ORNL, U.S. Dept. of Energy

As the United States shifts away from fossil-fuel-burning cars and trucks, scientists at the Department of Energy’s Oak Ridge and Argonne national laboratories are exploring options for another form of transportation: trains. The research focuses on zero-carbon hydrogen and other low-carbon fuels as viable alternatives to diesel for the rail industry.

This image from Sept. 30, 2022, shows how the Federal Emergency Management Agency used ORNL's USA Structures data along with new satellite images to identify structures that were destroyed in Lee County, Florida, during Hurricane Ian. Credit: ORNL, U.S. Dept. of Energy

Over the past seven years, researchers in ORNL’s Geospatial Science and Human Security Division have mapped and characterized all structures within the United States and its territories to aid FEMA in its response to disasters. This dataset provides a consistent, nationwide accounting of the buildings where people reside and work.

Susan Hubbard, ORNL’s deputy for science and technology, and Ricardo Marc-Antoni Duncanson, founder of Marc-Antoni Racing, celebrated the company's licensing of ORNL-developed technologies during an event on Oct. 17. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Marc-Antoni Racing has licensed a collection of patented energy storage technologies developed at ORNL. The technologies focus on components that enable fast-charging, energy-dense batteries for electric and hybrid vehicles and grid storage.

The AI-driven HyperCT platform has three primary points of articulation that can rotate a sample in almost any direction, eliminating the need for human intervention and significantly reducing lengthy experiment times. Credit: Genevieve Martin, ORNL/U.S. Dept. of Energy

Oak Ridge National Laboratory researchers are developing a first-of-its-kind artificial intelligence device for neutron scattering called Hyperspectral Computed Tomography, or HyperCT.

Burak Ozpineci, a Corporate Fellow and section head of Vehicle and Mobility Systems Research at Oak Ridge National Laboratory, is one of six international recipients of the eighth Nagamori Award recognizing his contributions to electrification in transportation. Credit: ORNL, U.S. Dept. of Energy

Burak Ozpineci, a Corporate Fellow and section head for Vehicle and Mobility Systems Research at Oak Ridge National Laboratory, is one of six international recipients of the eighth Nagamori Award.

Oak Ridge National Laboratory researchers developed an invertible neural network, a type of artificial intelligence that mimics the human brain, to improve accuracy in climate-change models and predictions. Credit: Getty Images

Oak Ridge National Laboratory researchers developed an invertible neural network, a type of artificial intelligence that mimics the human brain, to improve accuracy in climate-change models and predictions.

Frontier has arrived, and ORNL is preparing for science on Day One. Credit: Carlos Jones/ORNL, Dept. of Energy

The Frontier supercomputer at the Department of Energy’s Oak Ridge National Laboratory earned the top ranking today as the world’s fastest on the 59th TOP500 list, with 1.1 exaflops of performance. The system is the first to achieve an unprecedented level of computing performance known as exascale, a threshold of a quintillion calculations per second.

A smart approach to microscopy and imaging developed at Oak Ridge National Laboratory could drive discoveries in materials for future technologies. Credit: Adam Malin/ORNL, U.S. Dept. of Energy

Researchers at ORNL are teaching microscopes to drive discoveries with an intuitive algorithm, developed at the lab’s Center for Nanophase Materials Sciences, that could guide breakthroughs in new materials for energy technologies, sensing and computing.

The online Fuel Economy Guide, compiled by ORNL researchers, provides simple tips to save at the pump including the Trip Calculator tool to better navigate vehicle choice and estimate mileage. Credit: Storyblocks

Oak Ridge National Laboratory researchers determined that for every 5 miles per hour that drivers travel over a 50-mph speed limit, fuel economy decreases by 7% and equates to paying an extra 28 cents per gallon at current.