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Genetic analysis revealed connections between inflammatory activity and development of atomic dermatitis, according to researchers from the UPenn School of Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory. Credit: Kang Ko/UPenn

University of Pennsylvania researchers called on computational systems biology expertise at Oak Ridge National Laboratory to analyze large datasets of single-cell RNA sequencing from skin samples afflicted with atopic dermatitis.

Samples of four unique materials hitched a ride to space as part of an effort by ORNL scientists to evaluate how each fares under space conditions. Credit: Zac Ward/ORNL, U.S. Dept. of Energy

To study how space radiation affects materials for spacecraft and satellites, Oak Ridge National Laboratory scientists sent samples to the International Space Station. The results will inform design of radiation-resistant magnetic and electronic systems.

High voltage power lines carry electricity generated by the Tennessee Valley Authority to ORNL. Credit: Dobie Gillispie/ORNL, U.S. Dept. of Energy

ORNL and the Tennessee Valley Authority, or TVA, are joining forces to advance decarbonization technologies from discovery through deployment through a new memorandum of understanding, or MOU.

An artist's rendering of the Ultium Cells battery cell production facility to be built in Spring Hill, Tennessee, which will employ 1,300 people. Recognizing the unique expertise of their organizations, ORNL, TVA, and the Tennessee Department of Economic and Community Development have been working together for several years to bring startups developing battery technologies for EVs and established automotive firms to Tennessee. Credit: Ultium Cells

ORNL, TVA and TNECD were recognized by the Federal Laboratory Consortium for their impactful partnership that resulted in a record $2.3 billion investment by Ultium Cells, a General Motors and LG Energy Solution joint venture, to build a battery cell manufacturing plant in Spring Hill, Tennessee.

A new process developed by Oak Ridge National Laboratory leverages deep learning techniques to study cell movements in a simulated environment, guided by simple physics rules similar to video-game play. Credit: MSKCC and UTK

Scientists have developed a novel approach to computationally infer previously undetected behaviors within complex biological environments by analyzing live, time-lapsed images that show the positioning of embryonic cells in C. elegans, or roundworms. Their published methods could be used to reveal hidden biological activity. 

ORNL scientists used an electron beam for precision machining of nanoscale materials. Cubes were milled to change their shape and could also be removed from an array. Credit: Kevin Roccapriore/ORNL, U.S. Dept. of Energy

Drilling with the beam of an electron microscope, scientists at ORNL precisely machined tiny electrically conductive cubes that can interact with light and organized them in patterned structures that confine and relay light’s electromagnetic signal.

QLAN submit - A team from the U.S. Department of Energy’s Oak Ridge National Laboratory, Stanford University and Purdue University developed and demonstrated a novel, fully functional quantum local area network, or QLAN, to enable real-time adjustments to information shared with geographically isolated systems at ORNL using entangled photons passing through optical fiber. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

A rapidly emerging consensus in the scientific community predicts the future will be defined by humanity’s ability to exploit the laws of quantum mechanics.

An ORNL-led team studied the SARS-CoV-2 spike protein in the trimer state, shown here, to pinpoint structural transitions that could be disrupted to destabilize the protein and negate its harmful effects. Credit: Debsindhu Bhowmik/ORNL, U.S. Dept. of Energy

To explore the inner workings of severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2, researchers from ORNL developed a novel technique.

Ultra Safe Nuclear Corporation has licensed a novel method to 3D print highly resistant components for use in nuclear reactor designs. USNC Executive Vice President Kurt Terrani, formerly of ORNL, said the novel method will allow the company to make parts with desired complex shapes more efficiently. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

A novel method to 3D print components for nuclear reactors, developed by the Department of Energy’s Oak Ridge National Laboratory, has been licensed by Ultra Safe Nuclear Corporation.

This protein drives key processes for sulfide use in many microorganisms that produce methane, including Thermosipho melanesiensis. Researchers used supercomputing and deep learning tools to predict its structure, which has eluded experimental methods such as crystallography.  Credit: Ada Sedova/ORNL, U.S. Dept. of Energy

A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory and the Georgia Institute of Technology is using supercomputing and revolutionary deep learning tools to predict the structures and roles of thousands of proteins with unknown functions.