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Frontier supercomputer

A multi-institutional team, led by a group of investigators at Oak Ridge National Laboratory, has been studying various SARS-CoV-2 protein targets, including the virus’s main protease. The feat has earned the team a finalist nomination for the Association of Computing Machinery, or ACM, Gordon Bell Special Prize for High Performance Computing-Based COVID-19 Research.

ORNL assisted in investigating proteins called porins, one shown in red, which are found in the protective outer membrane of certain disease-causing bacteria and tether the membrane to the cell wall. Credit: Hyea (Sunny) Hwang/Georgia Tech and ORNL, U.S. Dept. of Energy

Scientists from Oak Ridge National Laboratory used high-performance computing to create protein models that helped reveal how the outer membrane is tethered to the cell membrane in certain bacteria.

U.S. Department of Energy Deputy Secretary Mark Menezes (right) tours the DemeTECH N95 filter material production area with Xin Sun, ORNL interim associate laboratory director (center) and Craig Blue, ORNL advanced manufacturing program manager. Credit: US Dept. of Energy

A collaboration between the ORNL and a Florida-based medical device manufacturer has led to the addition of 500 jobs in the Miami area to support the mass production of N95 respirator masks.

Emma Betters Thumbnail

Growing up in Florida, Emma Betters was fascinated by rockets and for good reason. Any time she wanted to see a space shuttle launch from NASA’s nearby Kennedy Space Center, all she had to do was sit on her front porch.

Quantum Science Center

The Department of Energy has selected Oak Ridge National Laboratory to lead a collaboration charged with developing quantum technologies that will usher in a new era of innovation.

Cars and coronavirus

Oak Ridge National Laboratory researchers have developed a machine learning model that could help predict the impact pandemics such as COVID-19 have on fuel demand in the United States.

Joe Hagerman is expanding connected neighborhood research at ORNL and envisions buildings of the future as resources capable of managing the flow and exchange of energy based on economic and market signals – a concept known as transactive energy. Credit: Carlos Jones/Oak Ridge National Laboratory, U.S. Department of Energy

Joe Hagerman, ORNL research lead for buildings integration and controls, understands the impact building technology innovations can have during times of crisis. Over a decade ago, he found himself in the middle of one of the most devastating natural disasters of the century, Hurricane Katrina.

Colorized micrograph of lily pollen

Oak Ridge National Laboratory researchers have built a novel microscope that provides a “chemical lens” for viewing biological systems including cell membranes and biofilms.

Computational biophysicist Ada Sedova is using experiments and high-performance computing to explore the properties of biological systems and predict their form and function, including research to accelerate drug discovery for COVID-19. Photo credit: Jason Richards, Oak Ridge National Laboratory, U.S. Dept. of Energy.

Ada Sedova’s journey to Oak Ridge National Laboratory has taken her on the path from pre-med studies in college to an accelerated graduate career in mathematics and biophysics and now to the intersection of computational science and biology

ORNL researchers are leading virtual STEM outreach activities, such as an Internet of Things demonstration in which participants in ORCSGirls control an LED board remotely.

COVID-19 has upended nearly every aspect of our daily lives and forced us all to rethink how we can continue our work in a more physically isolated world.