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Rob Moore II, INTERSECT Initiative Director, peers into one of the instruments in the Quantum Information Science Research Center

Rob Moore is a leader in autonomous science at ORNL, where he advances AI-driven, self-driving laboratory systems to accelerate materials discovery. Building on his work with the INTERSECT initiative, he now leads efforts toward fully autonomous research through the Labs of the Future program, supporting DOE’s broader Genesis Mission.

Grayscale comparison of surface textures showing real vs. synthetic images at different parameter settings, arranged in rows and columns.

ORNL researchers developed a machine learning model that generates realistic tungsten microstructure images, helping fill gaps in costly experimental data. The approach supports virtual experiments to design more durable fusion reactor components and reduce maintenance costs.

 

Close-up of a scientist examining a microscope instrument through a glass panel with green laser light inside

Yongtao Liu is an R&D staff member at Oak Ridge National Laboratory’s Center for Nanophase Materials Sciences (CNMS). In the Data NanoAnalytics Group, he is helping nanomaterials research move toward experiments that can run with far less handholding. 

Concrete dam with water spilling down one section into a calm river below, surrounded by trees

Researchers at Oak Ridge and Pacific Northwest national laboratories have partnered with Smith-Root Inc. to commercialize “eDNA-bot,” a patented, autonomous aquatic robot that collects and analyzes environmental DNA in real time using artificial intelligence. Developers say the technology could enable continuous, lower-cost biological monitoring for hydropower licensing, invasive species detection and wastewater pathogen monitoring.

Electron beam knocking a carbon atom out of a graphene lattice.

Researchers at ORNL are pushing the boundaries of science by combining artificial intelligence, automation and leading-edge imaging technology in a push toward autonomous experimentation. By leveraging the strengths of each of these elements in coordination with human intuition, they hope to create autonomous workflows that enhance researchers’ abilities to answer some of the toughest questions in science. 

Kashif Nawaz, head of the Building Technologies Research Section, and Wes Brewer, senior research scientist in the National Center for Computational Sciences, walk through the energy plant that supports the Frontier data center.

ORNL is announcing the creation of the Institute for Next-Generation Data Centers, a new national institute dedicated to advancing the design, operation and integration of artificial intelligence data centers into the United States’ energy system. 

Industrial robotic arm depositing layered composite material to form a square container on a movable table inside a manufacturing facility. The robot end effector is positioned above the partially built structure, with cables, equipment, and safety signage visible in the background.

ORNL has developed an innovative extrusion system that combines multiple 3D-printing extruders into a single, high-output stream via specially designed nozzles. This system matches the speed of larger extruders while providing greater flexibility, precision and multi-material printing capabilities.

Illustration of a flexible, layered purple material connected to a battery and light, with yellow particles moving through the layers to represent electrical charge flow in an energy-storage or electroactive material.

Researchers at ORNL have developed an innovative energy storage system design that introduces a safer, more efficient method for electrical charge transfer. The research team’s success is encouraging for next-generation energy storage systems that could help meet growing energy demands. 

A scanning tunneling microscope and machine learning algorithm autonomously search for atomic structures. This image shows a vacancy defect on europium zinc arsenide.

A research team led by Oak Ridge National Laboratory has developed a new method to uncover the atomic origins of unusual material behavior. This approach uses Bayesian deep learning, a form of artificial intelligence that combines probability theory and neural networks to analyze complex datasets with exceptional efficiency. 

Multiple circles surround a data set with green in the middle, orange on the outer ring, followed by blue at the bottom, green to the right and purple to the left. There are images in the background of ORNL's campus

ORNL has developed a network of autonomous science laboratories outfitted with state-of-the-art artificial intelligence and robotic systems and connected to the lab’s world-class user facilities. The goal is to supercharge the research process while producing scientific breakthroughs that would be unachievable in a traditional setting.