 |
 |
|
|
B=Working Paper
An authored manuscript prepared as support documentation for a Committee activity.
Publication of working papers does not require Commission review and approval.
C=Consensus Paper
An unauthored document prepared and published by the Commission as a whole. These reports
represent a consensus of the Commission's opinion on a specific topic.
D=Status or Meeting Paper
An unauthored or authored description of an ICPEMC sponsored meeting or a request for data
for a specific subject of ICPEMC interest.
0002.A
Matter, B. E., Kilbey, B. J., Drake, J., Hollaender, A., Ramel, C., Ray, V., and Sundaram,
K.(1979): Advice on screening of chemicals for mutagenicity.
Mutation Res., 64, 155-158; Biol. Zblatt, 98,473-475.
0003.A
Bridges, B. A., Clemmesen, J., and Sugimura, T.(1979): Cigarette smoking - Does it carry a
genetic risk? Mutation Res., 565, 71-81.; Biol. Zblatt, 98, 33-343.
0004.B
Clayson, D. B.(1980): Comparison between in vitro and in vivo tests for carcinogenicity.
Mutation Res., 75, 205-213.; Biol. Zblatt, 99, 87-94.
0005.B
Wright, A. S.(1980): The role of metabolism in chemical mutagenesis and chemical
carcinogenesis. Mutation Res., 75, 215-241.; Biol. Zblatt, 99, 207-304.
0006.A
Jansen, J. D., Clemmesen, J., and Sundaram, K.(1980): Isoniazid - an attempt at retrospective
prediction. Mutation Res., 76, 85-112;
Biol. Zblatt, 99, 453-479.
0007.A
Ramel, C., Drake, J., and Sugimura, T.(1980): An evaluation of the genetic toxicity of
dichlorvos. Mutation Res., 76, 297-309; Biol. Zblatt, 100 (1981),
75-87.
0008.B
Clayson, D. B.(1981): Carcinogens and carcinogenesis enhancers. Mutation Res., 86, 217229.;
Biol. Zblatt, 101 (1982) 285-295.
0009.B
Brookes, P.(1981): Critical assessment of the value of in vitro cell transformation for predicting
in vivo carcinogenicity of chemicals. Mutation Res., 86, 233-242.; Biol. Zblatt, 100, 421-430.
0010.B
Howard-Flanders, P.(1981): Mutagenesis in mammalian cells. Mutation Res., 86, 307-327.; Biol.
Zblatt, 100, 537-558.
0011.B
Clemmesen, J.(1981): Epidemiological studies of the possible carcinogenicity of hair dyes.
Mutation Res., 87, 63-79; Biol. Zblatt, 100 (1982) 413-427.
O012.B
Mohn, G. R.(1981): Bacterial systems for carcinogenicity testing. Mutation Res., 87, 191210.;
Biol. Zblatt, 102 (1983) 72-95.
0013.A
Sram, R. J., Tomatis, L., Clemmesen, J:, and Bridges, B. A.(1981): An evaluation of the genetic
toxicity of epichlorohydrin. Mutation Res., 87, 299-319; Biol. Zblatt, 102 (1983) 603620.
0014.B
Lyon, M.F.( 1981): Sensitivity of various germ-cell stages to environmental mutagens. Mutation
Res., 87, 321-345.; Biol. Zblatt, 102 (1983) 211-228.
0015.A
Bridges, B. A:, Greaves, M., Polani, P. E., and Wald, N.(1982): Do treatments available for
psoriasis patients carry a genetic or carcinogenic risk? Mutation Res., 86, 279-304.; Biol. Zblatt,
101, 533-566.
0016.B
Clemmesen, J.(1982): Mutagenicity and teratogenicity of vinyl chloride monomer (VCM).
epidemiological evidence. Mutation Res., 98, 95-100.
0017.B
Sivak, A.(1982): An evaluation of assay procedures for detection of tumor promotors. Mutation
Res., 98, 377-387.; Biol. Zblatt, 102 (1983) 211-229.
0018.B
Purchase, I. F. H.(1982): An appraisal of predictive tests for carcinogenicity. Mutation Res., 98,
53-71.; Biol. Zblatt, 102 (1983) 717-74.
0019.C
Mutagenesis testing as an approach to carcinogenesis. (1982). Mutation Res., 99, 73-91.
0020.B
Matsunaga, E.(1982): Perspectives in mutation epidemiology: 1. Incidence and prevalence of
genetic disease (excluding chromosomal aberrations) in human populations. Mutation Res., 99,
95-128; Biol. Zblatt, 103 (1984) 83-110.
0021.B
Hook, E.B.(1982): Perspectives in mutation epidemiology: 2. Epidemiologic and design aspects
of studies of somatic chromosome breakage and sister-chromatid exchange. Mutation Res., 99,
373-382; Biol. Zblatt, 103 (1984), 183-192.
0022.D
Sobels, F. H.(1983): Seven years ICPEMC, The International Commission for Protection against
Environmental Mutagens and Carcinogens, 15th International Congress of Genetics, New Delhi,
India, December 12-21.
0023.B
Streisinger, G.(1983): Extrapolation from species to species and from various cell-types in
assessing risks from chemical mutagens. Mutation Res., 114, 93-105.; Biol. Zblatt, 103 (1984)
195-204.
0024.A
Rarnel, C.(1983): Polygenic effects and genetic changes affecting quantitative traits. Mutation
Res., 114, 107-116; Biol. Zblatt, 103 (184) 313-32 .
0025.C
Screening strategy for chemicals that are potential germ-cell mutagens in mammals. (1983).
Mutation Res., 114, 117-177.
0026.C
Regulatory approaches to the control of environmental mutagens and carcinogens. (1983).
Mutation Res., 114, 179-216.
0027.B
Hook, E. B.(1983): Perspectives in mutation epidemiology: 3. Contribution of chromosome
abnormalities to human morbidity and mortality and some comments upon surveillance of
chromosome mutation rates. Mutation Res., 114, 389-423; Biol. Zblatt, 103 (1984), 679-705.
0028.B
Miller, J. R.(1983): Perspectives in mutation epidemiology: 4. General principles and
considerations. Mutation Res., 114, 425-447; Biol. Zblatt, 103 (1984), 559-578.
0029.B
Matsunaga, E.(1983): Perspectives in mutation epidemiology: 5. Modern medical practice versus
environmental mutagens; their possible dysgenic impact. Mutation Res,, 114, 449-457; Biol.
Zblatt, 103 (1984), 439-446.
0030.B
Ashby, J.(1983): The unique role of rodents in the detection of possible human carcinogens
and mutagens. Mutation Res., 115, 177-213.
0031.C
Estimation of genetic risks and increased incidence of genetic disease due to environmental
mutagens. (1983). Mutation Res., 115, 255-291.; Biol. Zblatt, 104 (1985) 57-87.
0032.B
Adler, I. D.(1983): Comparison of types of chemically induced genetic changes in mammals.
Mutation Res., 115, 293-321.
0033.C
Mutation Epidemiology: Review and recommendations. (1983). Mutation Res., 123, 1-11.;
Biol. Zblatt, 104 (1985) 205-213.
0034.B
Ehrenberg, L., Moustacchi, E., and Osterman-Golkar, S.(1983): Dosimetry of genotoxic agents
and dose-response relationships of their effects. Mutation Res., 123, 121-182.
0035.A
Ehling, U. H., Averbeck, D., Cerutti, P. A., Friedman, J., Greim, H., Kolbye, A. C., and Mendelsohn, M. L.(1983): Review of the evidence for the presence or absence of thresholds in the induction of genetic effects by genotoxic chemicals. Mutation Res., 123, 281-341.
0036.B
Mulvihill, J. J., and Czeizel, A.(1983): Perspectives in mutation epidemiology: 6. A 1983 view
of sentinel phenotypes. Mutation Res., 123, 345-361; Biol. Zblatt, 104 (1985), 457-470.
0037.D
Jansen, J. D.(1984): The International Commission for Protection against Environmental
Mutagens and Carcinogens (ICPEMC): The first seven years. Regulatory Toxicology and
Pharmacology, 4, 138-144.
0038.A
Upton, A. C., Clayson, D. B., Jansen, J. D., Rosenkranz,. H. S., and Williams, G. M.(1984):
Differentiation between genotoxic and nongenotoxic carcinogens. Mutation Res., 133, 1-49;
Biol. Zblatt, 104 (1985) 417-453.
0039.C
Guide to Short-term Tests for Detecting Mutagenic and Carcinogenic Chemicals. (1985).
Environmental Health Criteria 51, World Health Organization, Geneva, 1985.
0040.D
Bridges, B. A., Lenoir, G., and Tomatis, L.(1985): Workshop on Ataxia-Telangiectasia
heterozygotes and cancer. Cancer Research, 45, 3979-3980.
0041.A
Mekler, P. H., Delehanty, J. T., Lohman, P. H. M., Brouwer, J., Putte, P.v.d., Pearson, P.,
Pouwels, P. H., and Ramel, C.(1985): The use of recombinant DNA technology to study gene
alteration. Mutation Res., 153, 11-55.; Biol. Zblatt, 104, 553-599.
0042.B
Clayson, D. B.(1985): Diet, Mutation and Cancer. Mutation Res., 154, 205-217; Biol. Zblatt, 105
(1986) 435-448.
0043.B
Bridges, B. A., and Mendelssohn, M. L.(1986): Recommendations for screening for potential
human germ cell mutagens: an ICPEMC Working Paper. In: Ramel, C., Lambert, B., and
Magnusson, J. (Eds.): Genetic Toxicology of Environmental Chemicals, Part B: Genetic
Effects and Applied Mutagenesis. Alan Liss, Inc., New York, 51-65.
0044.B
Brusick, D., Ashby, J., de Serres, F., Lohman, P.H.M, Matsushita, T., Matter, B. E.,
Mendelssohn, M. L., and Waters, M. D.(1986): Weight-of-evidence scheme for evaluation and
interpretation of short-term results. In: Ramel, C., Lambert, B., and Magnusson, J. (Eds.):
Genetic Toxicology of Environmental Chemicals, Part B: Genetic Effects and Applied
Mutagenesis. Alan Liss, Inc., New York, 121-129.
0045.A
ICPEMC Perspectives on the scientific basis of risk assessment in genetic toxicology. Bridges,
B. A.(1986). In: Oftedal, P., and Brogger, A. (Eds.): Risk and Reason: Risk assessment in
relation to environmental mutagens and carcinogens. Alan Liss, Inc., New York, 175-182.
0046.D
Delehanty, J., White, R. L., and Mendelssohn, M, L.(1986): Approaches to determining mutation
rates in human DNA. Mutation Res., 167, 215-232,
0047.A
Clayson, D.B. and Krewski, D.(1986): The concept of negativity in experimental carcinogenesis.
Mutation Res., 167, 233-240.
0048.A
Ramel, C., Alekperov, U. K., Ames, B. N., Kada, T., and Wattenberg, L. W.(1986): Inhibitors of
mutagenesis and their relevance to carcinogenesis. Mutation Res., 168, 47-65; Biol. Zblatt, 105,
543-562.
0049.D
Scott, D.(1986): Announcement - Genotoxicity in vitro under extreme culture conditions: An
ICPEMC investigation. Mutation Res., 171, 189.
0050.D
Evans, H. J., Lyon, M. F., and Czeizel, A.(1986): Is the incidence of Down Syndrome
increasing? Mutation Res., 175, 263-266.
0051.A
Bridges, B. A.(1987): Are somatic mutations involved in atherosclerosis? Mutation Res., 182,
301-302.
0052.A
Clayson, D. B.(1987): The need for biological risk assessment in reaching decisions about
carcinogens. Mutation Res., 185 (3), 243-269.
0053.B
Czeizel, A., and Kis-Varga, A.(1987): Mutation surveillance of sentinel anomalies in Hungary, 1980-1984. Mutation Res., 186, 73-79; Biol. Zblatt, 107 (1988) 447-453.
0054.A
Bridges, B. A.(1987): Alcohol as a mutagenic agent; Report of an ICPEMC expert group.
Mutation Res., 186 (3), 173-174.
0055.C
Conclusions on the genotoxicity of alcohol and recommendations for further work. (1987).
Mutation Res., 186 (3), 175-17.
0056.B
Obe, G., and Anderson, D.(1987): Genetic effects of ethanol. Mutation Res., 186 (3), 177
200.
0057.B
Lieber, C. S., Baraona, E., Leo, M. A., and Garro, A.(1987): Metabolism and metabolic effects of
ethanol, including interaction with drugs, carcinogens and nutrition. Mutation Res., 186 (3),
201-233.
0058.B
Eriksson, C. J. P.(1987): Human acetaldehyde levels: aspects of current interest. Mutation Res.,
186 (3), 235-240.
0059.B
Eriksson, C. J. P.(1987): Genetic aspects of the relation between alcohol metabolism snd
consumption in humans. Mutation Res., 186 (3), 241-247.
0060.B
von Wartburg, J. P.(1987): Acute aldehyde syndrome and chronic aldehydism. Mutation Res.,
186 (3), 249-259.
0061.B
Swarm, P. F., Graves, R. J., and Mace, R.(1987): Effect of ethanol on nitrosamine metabolism
and distribution; Implications for the role of nitrosamines in human cancer and for the influence
of alcohol consumption on cancer incidence. Mutation Res., 186 (3), 261267.
0062.B
Gavaler, J. S., and Van Thiel, D. H.(1987): Reproductive consequences of alcohol abuse: males
and females compared and contrasted. Mutation Res., 186 (3), 269-277.
0063.A
Banbury Report No. 30 (1988). Lambert, M. E., McDonald, J. F., Weinstein, I.B. (Eds.):
Eukaryotic Transposable Elements as Mutagenic Agents. Cold Spring Harbor Laboratory Press,
Cold Spring Harbor, New York.
0064.B
G.R. Douglas, Blakey, D. H., and Clayson, D. B.(1988): Genotoxicity carcinogens: An analysis.
Mutation Res., 196, 83-93.
0065.A
de Serres, F. J.(1988): Heterozygous Effects of Multilocus Deletions. Mutation Res., 196,95-99.
0066.A
Carrano, A. V., and Natarajan, A. T.(1988): Considerations for population monitoring using
cytogenetic techniques. Mutation Res., 204, 379-406.
0067.C
Testing for mutagens and carcinogens: the role of short-term genotoxicity assays. A report
prepared by ICPEMC. (1988). Mutation Res., 205, 3-12.
0068.A
Clayson, D. B.(1989): Can a mechanistic rationale be provided for non-genotoxic carcinogens
identified in rodent bioassays? Mutation Res., 221, 53-67.
0069.B
Kis-Varga, A., Rudas, T., and Czeizel, A.(1990): A new approach to germinal mutation
surveillance: pair-wise evaluation of component elements in unidentified multiple congenital
abnormalities. Mutation Res., 238, 87-97.
0070.B
Lohman, P. H. M., Mendelssohn, M. L., Moore, D.H. II, Waters, M. D., and Brusick, D.J.(
1990): The assembly and analysis of short-term genotoxicity test data: an ICPEMC Committee 1
Working Paper. In: Mendelssohn, M.L. and Albertini, R.J.(Eds.): Mutation and the Environment,
Part D. Wiley-Liss, Inc., New York, 283-294.
0071.A
Babury Report No. 34 (1990).
Allen, .W., Bridge, B. A., Lyon, M. F., Moses, M.J., Russell, L.
R., (Eds.):
Biology of Mammalian Germ Cell Mutagenesis. Cold Spring Harbor Laboratory Press,
Cold Spring Harbor, New York.
0072.B
Nesnow, S.(1990): A multi-factor ranking scheme for comparing the carcinogenic
activity of chemicals. Mutation Res., 239, 81-115.
0073.A
The possible involvement of somatic mutations in the development of atherosclerotic
plaques. (1990).
Bridges, B. A.: Preamble, Mutation Res., 239, V
Bridges, B. A., Bowyer, D. E., Hansen, E. S., Penn A., and Wakabayashi, K.:
Conclusions and Recommendations. Mutation Res., 239, 143-148;
Atherosclerosis (1991),89, 255-261.
0074.B
Penn, A.(1990): Mutational events in the etiology of arteriosclerotic plaques. Mutation
Res., 239, 149-162.
0075.B
Hansen E. S.(1990): Shared risk factors for cancer and atherosclerosis - a review of the
epidemiological evidence. Mutation Res., 239, 163-179,
0076.B
Wakabayashi, K.(1990): Animal studies suggesting involvement of mutagen/carcinogen
exposure in atherosclerosis. Mutation Res., 23 , 181-187.
0077.A
Kramers, P. G.N., Gentile, J.M., Gryseels, B. J. A.M., Jordan, P., Katz, N., Mott, K. E.,
Mulvihill, J.J., Seed, J. L., and Frohberg, H.(1991): Review of the genotoxicity and
carcinogenicity of antischistosomal drugs; is there a case for a study of mutation
epidemiology Mutation Res., 257, 49-89.
0078.A
Clayson, D. B., and Arnold, D. L.(1991): The classification of carcinogens identified in
the rodent bioassay as
potential risks to humans: What type of substance should be tested next? Mutation Res.,
257, 91-106.
0079.A
Scott, D., Galloway, S. M., Marshall, R. R., Ishidate, M. Jr., Brusick, D., Ashby, J., and
Myhr, B. C.(1991): Genotoxicity under extreme culture conditions. Mutation Res., 257,
145-204.
0080.B
Angres, G., and Beth, M.(1991): Effects of dietary constituents on carcinogenesis in different tumor models: An overview from 1975 to 1988. Human Nutrition, Vol. 7, 337-487,
Cancer and Nutrition, Plenum Publishing Corporation, New York, New York.
0081.A
Brusick, D. J., Ashby, J., deSerres, F. J., Lohman, P. H. M., Matsushita, T., Matter, B. E.,
Mendelssohn, M. L., Moore, D.H. II, Nesnow, S., and Waters, M. D.(1992): A method for
combining and comparing short-term genotoxicity test data: Preface. Mutation Res., 266, 16.
0082.B
Lohman, P. H. M., Mendelssohn, M. L., Moore, D.H. II, Waters, M. D., Brusick, D.J., Ashby, J.,
and Lohman, W. J. A.(1992): A method for combining and comparing short-term genotoxicity
test data: The basic system. Mutation Res., 266, 7-25.
0083.B
Moore H, D. H., Mendelssohn, M.L,, and Lohman, P. H.M.( 1992): A method for combining and
comparing short-term genotoxicity test data: The optimal use of dose information. Mutation Res.,
266, 27-42.
0084.B
Mendelsohn, M. L., Moore, D.H. II, and Lohman, P. H. M.(1992): A method for combining and
comparing short-term genotoxicity test data: Results and interpretation. Mutation Res.,
266,43-60.
0085.A
Murphy, J. C., Kaden, D. A., Warren, J., Sivak, A.(1993): Power frequency electric and
magnetic fields: A review of genetic toxicology. Mutation Res., 296, 221-240.
0086.A
Czeizel A.(1993): Intrauterine growth retardation as a potential endpoint in mutation
epidemiology. Mutation Res., 296, 211-219.
0087.A
Wurgler, F. E.(1992): Recombination and gene conversion. Mutation Res. 284, 3-14.
0088.C
Assessing the risk of genetic damage (1992): Brusick, D. J., Gopalan, H. N. B., Heseltine, E.,
Huismans, J. W., and Lohman, P.H.M (Eds.). Hodder & Stoughton, Gaborone, Botswana.
0089.A
Clayson, D. B., Mehta, R., Iverson, F.(1994): Oxidative DNA damage - The effects of certain
genotoxic and operationally non-genotoxic carcinogens. Mutation Res., 317, 25-42.
0090.B
Bridges, B. A.(1994): Spontaneous mutation and its place in risk assessment for chemical
mutagens. Report of an ICPEMC Committee. Mutation Res., 304, 3-11.
0091.B
Bridges, B. A.(1994): Spontaneous mutation: some conceptual difficulties. Mutation Res., 304,
13-17.
0092.B
Glickman, B. A., Saddi, V. A., Curry, J.(1994): Spontaneous mutations in mammalian cells.
Mutation Res., 304, 19-32.
0093.B
Cole, J., Skopek k, T. R.(1994): Somatic mutation frequency, mutation rates and mutational
spectra
in the human population in vivo. Mutation Res., 304, 33-105.
0094.B
Favor, J.(1994): Spontaneous mutations in germ cells of the mouse: estimates of mutation
frequencies and a molecular characterization of mutagenic events. Mutation Res., 304, 107118.
0095.B
Mohrenweiser, H.(1994): Impact of the molecular spectrum of mutational lesions on estimates of
germinal gene mutation rates. Mutation Res., 304, 119-137.
0096.B
Sankaranarayanan, K.(1994): Estimation of genetic risks of exposure to chemical mutagens:
relevance of data on spontaneous mutations and of experience with ionizing radiation. Mutation
Res., 304, 139-158.
0097.B
Ashby, J.(1994): Two million rodent carcinogens? The role of SAR and QSAR in their detection.
Mutation Res., 305, 3-12.
0098.B
Vogel, E. W.(1994): The subtlety of alkylating agents. Mutation Res., 305, 13-32.
0099.B
Klopman, G. (1994): Approaches to SAR in Carcinogenesis and mutagenesis. Mutation Res., 305,
33-46.
0100.B
Enslein, K.(1994): Use of SAR in computer-assisted predication of carcinogenicity and
mutagenicity of chemicals by the TOPKAT program. Mutation Res., 305, 47-61.
0101.B
Debnath, A.(1994): The importance of the hydrophobic interaction in the mutagenicity of
organic compounds. Mutation Res., 305, 63-7 .
0102.B
Rosenkranz, H., Klopman, G., and Ashby, J.(1994): Structural implications of the ICPEMC
method for quantifying genotoxicty data. Mutation Res., 305, 99-116.
0103.B
Richard, A.(1994): Application of SAR methods to non-congeneric data bases associated with
carcinogenicity and mutagenicity: issues and approaches. Mutation Res., 305, 73-97.
0104.B
Olshan, A. F., Mattison, D. R., Zwanenburg, T. S. B.(1994): Cyclosporine A: Review of the
genotoxicity and potential for adverse human reproductive and developmental effects. Mutation
Res., 317, 163-173.
0105.B
Favor, J., Malling, H., Layton, D., Sega, G., Wassom, J., Burkhart J., Douglas, G., Dearfield, K.,
and Brusick, D.(1994): Genetic risk extrapolation from animal data to human disease: A taskgroup
report of the International Commission for Protection Against Environmental Mutagens and
Carcinogens (ICPEMC). Mutation Res., 330, 23-34.
0106.A
Methods for genetic risk assessment (1994): Brusick, D.J. (Ed.). CRC Press, Inc., Lewis
Publishers, Boca Raton, Florida.
0107.C
Brusick, D.J. (1994): Series: Current issues in mutagenesis and carcinogenesis, No. 39, Letter to
the Editor. Mutation Res., 319, 243-244.
0108.B
Anderson, R. D., Berger, N.A. (1994): Mutagenicity and carcinogenicity of topoisomerase
interactive agents. Mutation Res., 309, 109-142.
0109.B
Kunz, B. A., Kohalmi, S. E., Kunkel, T. A., Mathews, C. K., McIntosh, E. M., Reidy, J.A.
(1994): Deoxyribonucleotide triphosphate levels: A critical
factor in the maintenance of genetic stability. Mutation Res., 318, 1-64.