A Partial Listing of Human Genome Project Resources
This list shows some of the resources developed or improved in the course
of the Human Genome Project. These are available for application to
research by many scientific disciplines, including mutation research.
1. Methods and Instrumentation
- Genetic Mapping
- Physical Mapping
- DNA Sequencing
- Model Organisms
- Informatics
- Robotics
- Enhanced PCR Methods (Single Sperm PCR) (Double PCR Haplotyping)
- FISH Applications
- Single Molecule Analysis
- Novel Sequencing Techniques
- Multiplexed Fluorescence Detector for Capillary Electrophoresis
- Improved Fluorescence Reagents
- Microfabricating Capillary Assays
- DNA Sequencing Chips
- Modified RFLP Approaches to Mutation Analysis
- Integrated Molecular Analysis of Gene Expression
- Identification of Gene Function by Footprinting
- Single-Strand Conformation Polymorphisms (SSCP)
- Heteroduplex Mapping Assays
- Oligonucleotide Ligation Assay
2. Other Resources
- Cosmid Libraries
- DNA Cloning/Vectors: MAC, PAC, BAC
- YAC Libraries
- STS Collections
- Infomatics/Software
- Communication Tools: Human Genome News (newsletter); World Wide Web
- Cell Lines From Patients With Genetic Diseases
- cDNA Libraries
- Mycobacterial Sequence Data
- Improved Multiplex Phagemid Vectors
- Test Data Sets for Sequence Assembly
- Complete STS Sequences With PCR Conditions
- Genetic Markers
- Saccharomyces Genome Database
- Drosophila Genome Database
- Human and Mouse P1 Libraries
- Cell Hybrids
- E. coli Genome Sequence Database
- C. elegans Genome Database
- Mouse Genome YAC Library
- Primers for Mouse SSLPS
- Training Programs
- Personnel Available for Collaboration
- Equipment for Automating Laboratories
- Genome Sequencing Database (GenBank, GSDB, EMBL, DDBJ)
- Genome Mapping Database (Human) - GDB
- DOE and NIH Human Genome Centers
- ORNL MOUSEMACUR Project for Developing Mouse Models for Study of Mutations
- ORNL - A Transgenic and Targeted Mutation Facility
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