| Area |
HGP Goal |
Standard Achieved |
Date Achieved |
| Genetic Map |
2- to 5-cM
resolution map
(600 – 1,500 markers) |
1-cM
resolution map
(3,000 markers)
|
September 1994 |
| Physical Map |
30,000 STSs |
52,000 STSs |
October 1998 |
| DNA Sequence |
95% of gene-containing part of human sequence finished to 99.99% accuracy |
99% of
gene-containing part of human sequence finished to 99.99% accuracy |
April 2003 |
| Capacity and Cost of Finished Sequence |
Sequence 500 Mb/year at < $0.25 per finished base |
Sequence >1,400
Mb/year at <$0.09 per finished base |
November 2002 |
| Human Sequence Variation |
100,000 mapped human SNPs |
3.7 million mapped human SNPs |
February 2003 |
| Gene Identification |
Full-length human cDNAs |
15,000
full-length
human cDNAs |
March 2003 |
| Model Organisms |
Complete genome sequences of
E. coli,
S. cerevisiae,
C. elegans,
D. melanogaster |
Finished genome sequences of
E. coli,
S. cerevisiae,
C. elegans,
D. melanogaster,
plus
whole-genome drafts of several others, including
C. briggsae,
D. pseudoobscura, mouse and rat |
April 2003 |
| Functional Analysis |
Develop genomic-scale technologies |
High-throughput oligonucleotide synthesis |
1994 |
| DNA microarrays |
1996 |
| Eukaryotic, whole-genome knockouts (yeast) |
1999 |
| Scale-up of two-hybrid system for protein-protein interaction |
2002 |
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of Biological and Environmental Research, Human
Genome Program