| An emerging gene map. More
than 250 genes have already been mapped to chromosome 19.
Those listed on the lower half of this illustration have
been assigned to specific cosmids and (except for those
marked with asterisks) have been ordered on the Livermore
physical map. Their positions are therefore known with
far greater accuracy than shown here. The geneslisted
above the chromosome have been mapped to larger regions
of the chromosome -- or merely localized to chromosome 19
generally -- and have not yet been assigned to cosmids in
the Livermore database. The text mentions several of the
most important genes mapped so far. Others include INSR,
which codes for an insulin receptor and is involved in
adult-onset diabetes; LDLR, a gene for a low-density
lipoprotein receptor involved in hypercholesterolemia;
and ERCC2, a DNA repair gene implicated in one form of
xeroderma pigmentosum. |
