|An emerging gene map. More than 250 genes have already been mapped to chromosome 19. Those listed on the lower half of this illustration have been assigned to specific cosmids and (except for those marked with asterisks) have been ordered on the Livermore physical map. Their positions are therefore known with far greater accuracy than shown here. The geneslisted above the chromosome have been mapped to larger regions of the chromosome -- or merely localized to chromosome 19 generally -- and have not yet been assigned to cosmids in the Livermore database. The text mentions several of the most important genes mapped so far. Others include INSR, which codes for an insulin receptor and is involved in adult-onset diabetes; LDLR, a gene for a low-density lipoprotein receptor involved in hypercholesterolemia; and ERCC2, a DNA repair gene implicated in one form of xeroderma pigmentosum.|
To Know Ourselveswas prepared at the request of the U.S. Department of Energy, Office of Health and Environmental Research, as an overview of the Human Genome Project.