Uncovering Microbial Genome Potential
DOE Microbial Genome Program Report
The list below was current as of January 2000. Please see http://microbialgenomics.energy.gov/organisms.shtml for a more current list of microbes being sequenced by grantees of the DOE Microbial Genome Program.
*Aquifex aeolicus (bacteria extremophile, 1.5 Mb): Potential for identifying high-temperature enzymes.
*Archaeoglobus fulgidus (archaea extremophile, 2.3Mb): Potential for identifying high-temperature and high-pressure enzymes; useful in oil industry.
*Borrelia burgdorferi (bacteria, 1.3 Mb): Human pathogen that causes Lyme disease. One linear chromosome (915 kb) supported by DOE. Entire genome published by TIGR.
Caulobacter crescentus (bacteria, 3.8 Mb): Potential for heavy-metal remediation in waste-treatment plant wastewater; simple developmental cycle.
Chlorobium tepidum (bacteria, 2.1 Mb): Photosynthetic; may play important role in Earth's overall carbon cycle.
Dehalococcoides ethenogenes (bacteria, less than 2 Mb): Degrades dangerous solvent trichloroethene to benign products.
*Deinococcus radiodurans (bacteria, 3 Mb): Survives extremely high levels of radiation; possesses DNA-repair capabilities for radioactive waste cleanup. Additional Abstracts: UWM, Uniformed Services University of the Health Sciences, PNNL.
Desulfovibrio vulgaris (bacteria, 1.7 Mb): High potential for bioremediation through metal and sulfate reduction.
*Halobacterium halobium plasmid (archaea, genome size 2 Mb, NRC100 plasmid size 190 kb): Potential for identifying high-salinity enzymes.
*Methanobacterium thermoautotrophicum (archaea, 1.7 Mb): Produces methane; plays role in earth's overall carbon cycle.
Methylococcus capsulatus (bacteria, 4.6 Mb): Uses methane as single carbon and energy source; generates enzymes that oxidize some pollutants; used commercially to produce biomass and other proteins of interest.
*Mycoplasma genitalium (bacteria, 580 kb): Human pathogen; serves as model for minimal set of genes sufficient for free-living existence.
Pseudomonas putida (bacteria, 5 Mb): High potential for bioremediation by reducing metal and pollutants.
**Pyrobaculum aerophilum (archaea extremophile, 1.8 Mb): Potential for identifying high-temperature enzymes.
Shewanella putrefaciens (bacteria, 4.5 Mb): Potential for degrading toxic organic wastes and for sequestering toxic metals.
*Sphingomonas aromaticivorans F199pNRC100 plasmid (bacteria, genome size est. 4 Mb; pNL1 plasmid size 184 kb): Deep-soil organism with potential for degrading toxic organic compounds.
#Synechococcus (bacteria, genome size undetermined): Photosynthetic; uses nitrate and ammonia as nitrogen sources.
*Thermotoga maritima (bacteria extremophile, 1.8 Mb): Potential for identifying high-temperature, high-pressure enzymes.
Thiobacillus ferrooxidans (bacteria, 2.9 Mb): Used in mining
industry to sequester iron and sulfide.
|The online presentation of this 2000 publication is a special feature of the Human Genome Project Information Web site.|