|
|
|
|
 |
 |
Spanning Disciplines, Advancing Knowledge Promoting Awareness, Progress, and Applications of the Human Genome Project |
Sponsored by the U.S. Department of Energy Human Genome Program
Human
Genome News Archive Edition |
Human Genome News, January-June 1997; 8:(3-4)
The Cancer Genome Anatomy Project (CGAP) of the National Cancer Institute (NCI) is set to go online (http://www.ncbi.nlm.nih.gov/CGAP/) with the first installment in its cancer gene catalog. The goal of CGAP, which began last year, is to develop new diagnostic tools based on understanding molecular changes that underlie all cancers. These tools eventually will help doctors develop and select treatments designed to fight specific cancers. Europe is establishing a similar program called the Cancer Gene Expression Program.
One of CGAP's short-term goals is to compile an index of all genes that are turned on during the cancer process. Such an index would allow scientists, for the first time, to create complete genetic profiles differentiating among normal, precancerous, and malignant cells. The index will feature EST sequences from 45 cDNA libraries of lung, colon, prostate, ovarian, and breast tumors. Data about the tumors and source libraries also will be presented.
DOE researchers are generating the bacterial clones needed to hold ESTs and longer cDNA fragments, and the Integrated Molecular Analysis of Gene Expression consortium will make them available to all researchers. DOE support stands at about $1 million. NCI is putting forward $4 million for the index, $6 million to develop gene-analysis technologies and generate long cDNAs, and $10 million to develop clinical applications for this research data. [Contact: robert_strausberg@nih.gov]
Back to Home Page
Back to Table of Contents
The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v8n3).
Last modified: Wednesday, October 29, 2003
Home * Contacts * Disclaimer
Document Use and Credits
Publications and webpages on this site were created by the U.S. Department of Energy Genome Program's Biological and Environmental Research Information System (BERIS). Permission to use these documents is not needed, but please credit the U.S. Department of Energy Genome Programs and provide the website http://genomics.energy.gov. All other materials were provided by third parties and not created by the U.S. Department of Energy. You must contact the person listed in the citation before using those documents.
Base URL: www.ornl.gov/hgmis
Site sponsored by the U.S. Department of Energy
Office of Science, Office
of Biological and Environmental Research, Human
Genome Program
