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Human Genome News Archive Edition

Human Genome News, April-June 1996; 7(6)

GDB Links to Mammalian Homology, Enzyme Function Data

Genome Database (GDB) has reestablished links from over 1500 GDB human gene entries to mammalian homology data within the Mouse Genome Database (MGD) and to over 400 enzyme entries within the ENZYME database. Both types of links are accessible from gene entries in GDB.

Although its primary focus is the mouse, MGD's homology data also includes gene symbols, chromosomal locations, and citations regarding numerous mammalian species. Mammalian homology data can be accessed from GDB by querying for a specific human gene (e.g., SOD1) and following the homology link to the relevant MGD entry.

ENZYME database entries include the reaction catalyzed, cofactors, links to the PROSITE database (protein sites and patterns), and detailed SWISS-PROT entries. ENZYME database links are from protein products rather than from gene entries themselves. For example, the enzyme link for the human SOD1 gene can be found by querying for this gene, choosing "Protein SUPEROXIDE DISMUTASE" from the Gene SOD1 entry, and then selecting the "EC: 1.15.1.1" link.

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Human Genome Program, U.S. Department of Energy, Human Genome News (v7n6).

Last modified: Wednesday, October 29, 2003

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