Progress, and Applications
of the Human Genome Project
Sponsored by the U.S. Department of Energy Human Genome Program
Human Genome News Archive Edition
Vol.12, Nos.1-2 February 2002
In the News
JGI Completes Draft Pufferfish Genome, Begins Poplar Sequencing
Great Potential Benefitsfor Health, Environment, Energy Security
Having completed the draft sequence of the pufferfish Fugu rubripes genome in collaboration with an international consortium, the Production Genomics Facility* of DOEs Joint Genome Institute (JGI) is sequencing and assembling the genome of the poplar (Populus) tree (www.jgi.doe.gov). Fugu already is providing clues for finding similar genes and control elements in humans; a detailed knowledge of the poplar genome also will lead to significant environmental and energy security benefits. Brief descriptions of both projects follow.
Comparing the two vertebrate genome sequences will allow the discovery of new human genes and important elements that control or regulate their activity. Fugu is the first animal genome to be assembled by whole-genome shotgun sequencing and made available }to the public. The sequencing consortium plans to publish an analysis and is making all sequence information freely available via the JGI Web site.
The project is sponsored by the Carbon Management and Sequestration Program of DOEs Biological and Environmental Research program. The agencys main interest in this work is to understand and provide the scientific foundation for eventually enhancing the molecular mechanisms involved in capturing and sequestering (storing) carbon.
Counter Global Warming
Because carbon is stored in plant tissues, large biological systems such as trees are the principal way to sequester CO2 already in the atmosphere. Fast-growing poplars and other similar plants that produce the most biomass per acre per year are the best choices for carbon sequestration. Furthermore, once genomic data are obtained and the mechanisms involved are understood better, these plants can be modified genetically to take up and retain more carbon in an inaccessible form when they decompose.
Enhance U.S. Energy Security
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Last modified: Wednesday, October 29, 2003
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