Progress, and Applications
of the Human Genome Project
Sponsored by the U.S. Department of Energy Human Genome Program
Human Genome News Archive Edition
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In this issue...
DOE '99 Oakland Highlights
In the News
Web, Other Resources, Publications
Improved Sample Prep System
Report from 1999 DOE Genome Meeting
Although the last decade has brought many advances in analytical instrumentation for characterizing complex biological samples, the technology for sample preparation has lagged behind. In an article in Analytical Chemistry [70, 1797-1801 (1998)], Richard Smith (PNNL) described a sample-cleanup microdialysis system that was integrated into the measurement instrumentation, greatly reducing the amount of sample required for analysis. Smith observed that the device has potential for rapidly identifying microorganisms by using mass spectrometry to detect characteristic biomarker species and for analyzing DNA using MS or automated PCR instrumentation.
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Last modified: Wednesday, October 29, 2003
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