|Genome Informatics Section
DOE Human Genome Program Contractor-Grantee Workshop
|79. Visualization, Navigation,
and Query of Genomes: The Genome Channel and Beyond
Morey Parang, Richard Mural, Manesh
Shah, Doug Hyatt, Miriam Land, Jay Snoddy, Edward C. Uberbacher, and the
Genome Annotation Consortium
We are developing and deploying a series of interface tools for visualizing and querying the reference human genome and other genomes assembled and annotated by the Genome Annotation Consortium (see related abstracts). The Genome Channel Browser is a Java viewer capable of representing a wide variety of genomic-sequence annotation and links to a large number of related information and data resources. It relies on a number of underlying data resources, analysis tools, and data-retrieval agents to provide an up-to-date view of genomic sequences as well as computational and experimental annotation.
The current version of the Genome Channel Browser provides a diverse set of functional features in a DNA sequence including PolyA sites, CpG islands, repetitive DNA, simple repeats, STSs, GRAIL2 and Genscan exons, as well as GRAIL-EXP and Genscan gene models and their respective protein translations. The underlying information and evidence for genes and other features is presented in a variety of text windows, graphics windows, and summary reports.
The new version of the Genome Channel Browser (v2.0) offers such improved user interface and additional capabilities as the following:
We are researching the feasibility of providing interfaces to additional types of analysis results, such as protein threading and structural classification that might provide clues to the functions of predicted genes. Other features being studied for future implementation and visualization include polymorphisms and mutations.
|Author Index||Sequencing Technologies||Microbial Genome Program|
|Search||Mapping||Ethical, Legal, & Social Issues|