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Genome Informatics Section
DOE Human Genome Program Contractor-Grantee Workshop
VII
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101. Arraydb: CGH-Array Tracking Database Donn Davy, Daniel Pinkel, Donna
Albertson, Steve Clark, Joel Palmer, Don Uber, Arthur Jones, Joe Gray,
and Manfred Zorn
In collaboration with the UCSF Cancer Center, we have developed a database to track data from all stages of the production and use of the CGH (Comparitive Genome Hybridization) expression array slides produced robotically by separate LBNL-Cancer Center collaboration. The system tracks clones or DNA and their sources as they are selected for use in the array, the DNA preparation, the microtiter plates, print-run specifications, slide-printing runs, and slides printed. Researchers then log experiments performed on slides, with the resulting slide-images and analyses written back to the database, providing results which link back to the original clone or DNA and its source. The system is implemented in an Oracle 8 database, served on the Web by a NetDynamics application server, providing a highly scaleable, flexible, and responsive solution. It is accessible from java-compatible web browsers, and can provide a fine-grained control of security and accessibility. |
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