Nuclear Medicine Program Publications
1999

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Peer-Reviewed Journal Articles, 1999

Bergstrom, K., Halldin, C., Savonen, A., Okubo, Y., Hiltunen, J., Nobuhara, K., Swahn, C.-G., Karlsson, P., McPherson, D. W., Knapp, F. F., Jr., Larsson, S., Schnell, P.-O. and Farde, L. "Iodine-123-Labelled Z-(R,R)-IQNP: A Potential Radioligand for Visualization of M1and M 2Muscarinic Acetylcholine Receptors in Alzheimer’s Disease," Eur. J. Nucl. Med., 26, 1482-1486 (1999).

Cagle, D. W., Kennel, S. J., Mirzadeh, S., Alford, J. M. and Wilson, L. J. " In Vivo Studies of Fullerne-Based Materials Using Endohedral Metallofullerne Radiotracers," Proc. Natl. Acad. Sci., 96, 5182-5187 (1999).

Davis, I. A., Glowienka, K. A., Boll, R. A., Deal, K. A., Brechbiel, M. W., Stabin, M., Bocksler, P. N., Mirzadeh S. and Kennel, S. J. "Comparison of 225Actinium Chelates: Tissue Distribution and Radiotoxicity," Nucl. Med. Biol., 26, 581-589 (1999).

Deal, K. A., Davis, I. A., Mirzadeh, S., Kennel, S. J. and Brechbiel, M. W. "Improved In Vivo Stability of Actinium-225 Macrocyclic Complexes," J. Med. Chem., 42, 2988-2992 (1999).

Kennel, S. J. Boll, R., Stabin, M., Schuller, H. M. and Mirzadeh, S. "Radioimmunotherapy of Micrometastases in Lung with Vascular Targeted 213Bi," Brit. J. Cancer, 80, 175-184 (1999).

Kennel, S. J., Lankford, P. K., Foote, L. J., Davis, I. A., Boll, R. A. and Mirzadeh, S. "Combination Vascular Targeted and Tumor Targeted Radioimmunotherapy," Cancer Biotherapy and Radiopharmaceuticals, 14, 371-379 (1999).

Kennel, S. J., Stabin, M., Yoriyaz, H., Brechbiel, M. and Mirzadeh, S. "Treatment of Lung Tumor Colonies with 90Y Targeted to Blood Vessels: Comparison with the "-Particle Emitter 213Bi," Nucl. Med. Biol., 26, 149-157 (1999).

Kennel, S. J., Stabin, M., Foote, L. J., Lankford, P. K.. Terzaghi-Howe, M., Patterson, H., Barkenbus, J., Popp, D. M., Boll, R. and Mirzadeh, S. "Toxicity and Microdosimetry for 213Bi Bound to Membranes of Monolayer and Speroid Cultures of Tumor Cells," Radiation Res., 151, 244-256 (1999).

Knapp, F. F., Jr., Guhlke, S., Beets, A. L., Lin, W.-Y., Stabin, M., Amols, H. and Weinberger, J. "Endovascular Beta Irradiation for Prevention of Restenosis Using Solution Radioisotopes: Pharmacologic and Dosimetric Properties of Rhenium-188 Compounds," Cardiovasc. Rad. Med., 1, 86-97 (1999).

Knapp, F. F., Jr. and Kropp, J. "BMIPP - Design and Development," Int. J. Cardiac Imaging, 15, 1-9 (1999).

Knapp, F. F., Jr., Beets, A. L., Mirzadeh, S., Alexander, C. W. and Hobbs, R. L. "Production of Medical Radioisotopes in the ORNL High Flux Isotope Reactor (HFIR) For Cancer Treatment and Arterial Restenosis Therapy After PTCA," Czech. J. Physics, 49, Suppl. S1-Part II, 799-809 (1999).

Lin, C.-P., Lin, W.-Y., Hsieh, B.-T., Ting, G., Wang, S.-J., Yen, T.-C., Knapp, F. F., Jr. and Yeh, S.-J. "Effect of Reaction Conditions on Preparation of Rhenium-188 Hydroxyethylidene Diphosphonate Complexes," Nucl. Med. Biol., 26, 455-459 (1999).

Kropp, J., Eisenhut, M., Lehmann, W. D., Ambrose, K. R., Knapp, F. F., Jr. and Franke, W.-G. "Pharmacokinetics and Metabolism of the Methyl-Branched Fatty Acid (BMIPP) in Animals and Man," J . Nucl. Med., 40, 1484-1491 (1999).

McPherson, D. W., Luo, H., Kropp, J. and Knapp, F. F., Jr. "Improved Radioiodination of 1,2-Dipalmitoyl-3-IPPA Via a Tributyltin Intermediate," J. Appl. Rad. Isot., 51, 411-417 (1999).

McPherson, D. W. and Knapp, F. F., Jr. "A Rapid and Simple SepPak® Method for Purification of Radioiodinated IQNP, A High Affinity mAChR Ligand for the Muscarinic Receptor," Nucl. Med. Biol., 26, 859-863 (1999).

Mokler, F. T., Lin, Q., Luo, H., McPherson, D. W., Ambrose, K. R., Beets, A. L. Bockisch, A., Kropp, J. and Knapp, Jr., F. F. "Dual-Label Studies with [I-125]-3(R)/[I-131]-3(S)-BMIPP Demonstrate Similar Metabolism in Rat Tissues," J. Nucl. Med., 40,1918-1927 (1999).

Sloof, G. W., Visser, F. C., Comans, E. F. I., van Eenige, M. J., Groeneveld, A. B. J., van der Vusse, G. J. and Knapp, Jr., F. F. "Relationship Between Uptake of a Dimethyl-Branched Fatty Acid and Heterogeneous Myocardial Blood Flow in Ischemic and Normal Canine Myocardium," J. Nucl. Med., 40, 1204-1215 (1999).

Thrash, T. P., Cagle, D. W., Alford, J. M., Wright, K., Ehrhardt, G. J., Mirzadeh, S. and Wilson, L. J. "Toward Fullerne-Based radiopharmaceuticals: High Yield Neutron Activation of Endohedral 165Ho Metallofullerenes," Chem. Phys. Lett., 12673 (1999).

Yu, J., Yin, D., Min, X., Guo, Z., Zhang, J., Wang, Y. and Knapp, F. F., Jr. "Preparation of [188Re]-Rhenium Sulfide Suspension and its Biodistribution Following Intra-Tumoral Injection in Mice," J. Lab. Cmpds. Radiopharm., 42, 233-243 (1999).

Weinberger, J., Giedd, K. N., Simon, A. D., Marboe, C., Knapp, F. F., Jr., Trichter, F. and Amols H. "Radioactive Beta-Emitting Solution-Filled Balloon Treatment Prevents Porcine Coronary Restenosis," Cardiovasc. Rad. Med., 1, 252-256 (1999).

Yu, J., Duanzhi, Y., Xiaofeng, M. Zili, G., Jiong, Z., Yongxian, W. and Knapp, F. F., Jr. "[188Re]Rhenium Sulfide Suspension: A Potential Radiopharmaceutical for Tumor Treatment Following Intra-Tumor Injection," Nucl. Med. Biol., 26, 573-579 (1999).

Zimmerman, B. E., Cessna, J. T., Unterweger, M. P., Li, A. N., Whiting, J. S. and Knapp, F. F., Jr. "A New Experimental Determination of the Dose Calibrator Setting for Rhenium-188," J. Nucl. Med., 40, 1508-1516 (1999).

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