Isotope Development Group's

Nuclear Medicine Program

Russ Knapp, Program Manager

The ORNL Nuclear Medicine Research Program follows a long tradition in developing useful diagnostic and therapeutic applications of radioisotopes. Our research focuses on the development of medical radioisotope processing techniques, radionuclide generator research and the development of new tissue-specific radiopharmaceuticals for diagnostic and therapeutic applications in nuclear medicine, oncology and interventional cardiology. Key strengths are in the areas of radiopharmaceutical chemistry, radiochemistry, radioisotope process research and biomedical applications. The ORNL High Flux Isotope Reactor (HFIR) represents an important resource which provides primarily neutron-rich radioisotopes. We are developing new processing procedures and also making important contributions in the development of new radionuclide generator systems which provide radioisotopes for various therapeutic applications in the areas of tumor therapy and diagnosis. We are actively collaborating with a variety of programs within ORNL and at universities, medical schools and other research institutions throughout the world. These Medical Cooperative Programs provide an important opportunity for further preclinical research and clinical evaluation of new agents developed in our ORNL program. The clinical evaluation and commercialization of new agents developed at ORNL illustrates the important transition of our new technologies from the laboratory to availability for routine clinical use.

Radioisotope Processing Technology and Radionuclide Generator Research


Development and Testing of New Tissue-Specific Radiopharmaceuticals

The Tungsten-188/Rhenium-188 Generator System and Development and Clinical Evaluation of Rhenium-188-Labeled Therapeutic Agents

Alpha Emitting Radioisotopes for Tumor Therapy

Medical Collaborative Programs, Technology Transfer Efforts, and Clinical Evaluation of ORNL Radiopharmaceuticals

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The Nuclear Medicine Program at ORNL

bullet4.jpg (672 bytes) Nuclear Medicine Staff
bullet4.jpg (672 bytes) Guests and Students
bullet4.jpg (672 bytes) Facilities and Resources
bullet4.jpg (672 bytes) Publications
bullet4.jpg (672 bytes) Clinical Studies
bullet4.jpg (672 bytes) New ORNL Technology
bullet4.jpg (672 bytes) The Tungsten-188/rhenium-188 Generator
bullet4.jpg (672 bytes) DOE Isotope Catalog
bullet4.jpg (672 bytes) DOE Isotope Order Form
bullet4.jpg (672 bytes) Procedures Manual (internal use only)
bullet4.jpg (672 bytes) Nuclear Medicine Home Page
bullet4.jpg (672 bytes) NSTD Home Page
bullet4.jpg (672 bytes) Disclaimers

This site was updated 03/15/2005
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