
Isotope Development Group's
Nuclear Medicine Program
Russ Knapp, Program Manager
The ORNL Nuclear Medicine Research Program follows a long
tradition in developing useful diagnostic and therapeutic applications of radioisotopes.
Our research focuses on the development of medical radioisotope processing techniques,
radionuclide generator research and the development of new tissue-specific
radiopharmaceuticals for diagnostic and therapeutic applications in nuclear medicine,
oncology and interventional cardiology. Key strengths are in the areas of
radiopharmaceutical chemistry, radiochemistry, radioisotope process research and
biomedical applications. The ORNL High Flux Isotope Reactor (HFIR) represents an
important resource which provides primarily neutron-rich radioisotopes.
We are developing new processing procedures and also making important contributions in the
development of new radionuclide generator systems which provide radioisotopes for various
therapeutic applications in the areas of tumor therapy and diagnosis. We are actively
collaborating with a variety of programs within ORNL and at universities, medical schools
and other research institutions throughout the world. These Medical Cooperative
Programs provide an important opportunity for further preclinical research and
clinical evaluation of new agents developed in our ORNL program. The clinical evaluation
and commercialization of new agents developed at ORNL illustrates the important transition
of our new technologies from the laboratory to availability for routine clinical use.
Radioisotope Processing
Technology and Radionuclide Generator Research
Development and Testing of New
Tissue-Specific Radiopharmaceuticals
The Tungsten-188/Rhenium-188
Generator System and Development and Clinical Evaluation of Rhenium-188-Labeled
Therapeutic Agents
Alpha Emitting Radioisotopes
for Tumor Therapy
Medical Collaborative Programs, Technology Transfer Efforts, and
Clinical Evaluation of ORNL Radiopharmaceuticals

The Nuclear Medicine Program at ORNL
Nuclear Medicine Staff
Guests and Students
Facilities and Resources
Publications
Clinical Studies
New ORNL Technology
The
Tungsten-188/rhenium-188 Generator
DOE Isotope Catalog
DOE Isotope Order Form
Procedures
Manual (internal use only)
Nuclear Medicine
Home Page
NSTD Home Page
Disclaimers
This site was updated 03/15/2005

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