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Provided by Oak Ridge National Laboratory;
A facility managed by UT-Battelle, LLC;
For the U.S. Department of Energy.
Recent Applications of Our Work
LMJ-SSP
Video of the Auto Surface Sampling Probe in use.
Making contact with the surface through automated control.Video of the HandsFree TLC/MS (c) software in use.
The probing tip scanned over a stamped text ("COPY") on paper and the image was reconstructed from MRM mass spectrometric signal of ink Rhodamine B used in the stamp.Video of the HandsFree TLC/MS (c) software in use.
General software operations for autonomous probing
DESI
OBMS Scan
A DESI probing: the probe is scanned over the text OBMS paper as seen within the software window for automated Analysis.OBMS Array
A DESI probing: the probe is scanned over an array of samples on spots on paper as seen within the software window for automated Analysis.
More Media / Presentations
Identification of Isomeric Phase II Drug Metabolites From Mouse Thin Tissue Sections using Liquid-Extraction Based Surface Sampling Mass Spectrometry
Vilmos Kertesz and Gary J. Van BerkelHigh Throughput Analysis of Capture Cards with a Liquid Microjunction Surface Sampling Probe/Electrospray Ionization Mass Spectrometry System
Matthew J. Walworth; Joseph J. Stankovich; Mariam S. ElNaggar; Chuck Witkowski; Jeremy L. Norris; Gary J. Van BerkelThin Layer Chromatography and Mass Spectrometry Coupled using Proximal Probe Thermal Desorption with Electrospray or Atmospheric Pressure Chemical Ionization
Olga S. Ovchinnikova and Gary J. Van Berkel
2009
Direct Analysis of RP HPTLC Separated Tryptic Protein Digests using a Liquid Microjunction Surface Sampling Probe/ESI-MS System.
Joshua F. Emory, Matthew J. Walworth, Gary J. Van Berkel, Michael Schulz and Susanne Minarik.Instrumentation for Atmospheric Pressure, Nanoscale Chemical Imaging via Tip-Enhanced, *Near-Field Desorption/Ionization Mass Spectrometry.
D. E. Goeringer, J. A. Bradshaw, K. A. Meyer, O. S. OvchinnikovaEvaluation of the Cellodextrin Profiles of the Enzymatic Digests of Switchgrass.
Bruce A. Tomkins, Gary J. Van Berkel, Timothy J. Tschaplinski, Nancy L. Engle
2008
Comparison of Drug Distribution Images from Thin Tissue Sections Obtained Using Desorption Electrospray Ionization Tandem Mass Spectrometry and Whole-Body Autoradiography.
Vilmos Kertesz, Gary J. Van Berkel, Marissa Vavrek, Kenneth A. Koeplinger, Bradley B. Schneider and Thomas R. CoveyEnhanced Performance of a Liquid Microjunction Surface Sampling Probe using ESI and APCI.
Gary J. Van Berkel, Vilmos Kertesz, Bradley B. Schneider, and Thomas R. CoveyFactors Affecting Signal Levels in HPTLC/DESI-MS of Dipeptides and Tryptic Peptides.
Arron Wolk, Sofie P. Pasilis, Vilmos Kertesz, Gary J. Van BerkelHPTLC/DESI-MS Imaging of Tryptic Protein Digests Separated in Two Dimensions.
Sofie P. Pasilis, Vilmos Kertesz, Gary J. Van Berkel, Michael Schulz, and Susanne Schorcht
2007
Imaging Surfaces by Desorption Electrospray Mass Spectrometry: Issues and Solutions.
Vilmos Kertesz and Gary J. Van BerkelEffect of Spray Plume Characteristics on Desorption and Ionization in DESI.
Sofie P. Pasilis, Vilmos Kertesz and Gary J. Van BerkelSurface Analysis and Chemical Imaging with DESI: Technology-Related Challenges and Solutions.
Vilmos Kertesz, Gary J. Van Berkel and Sofie P. PasilisPerformance Study of an Extended Length Particle Discriminator Interface for Desorption Electrospray Ionization.
Gary J. Van Berkel, Vilmos Kertesz, Bradley B. Schneider, and Thomas R. Covey
2006
Using the Inherent Electrochemistry in a Microfabricated Nanospray Emitter System for Analytical Advantage.
Vilmos Kertesz and Gary J. Van BerkelSurface Sampling Mass Spectrometry with Spray Ionization Interfaces.
Michael Ford.
2005
The Electrochemistry of Electrospray: Tales of Roads Less Traveled.
Gary J. Van BerkelTLC and APCI-MS Coupled Using a Surface Sampling Heated Nebulizer Probe.
Keiji G. Asano, Michael J. Ford and Gary J. Van BerkelAutomated Surface Sampling Electrospray Mass Spectrometry.
Vilmos Kertesz, Michael J. Ford and Gary J. Van BerkelQuantitative TLC/MS of Caffeine Using Surface Sampling Electrospray Ionization Mass Spectrometry.
Bruce A. Tomkins, Gary J. Van Berkel, Michael J. Ford, Michael A. DeibelDesorption Electrospray Ionization for the Analysis of Analytes on Surfaces.
Gary J. Van Berkel, Michael J. Ford, Michael A. Deibel
2004
Spray Ionization Interfaces for Surface Sampling with Mass Spectrometry.
Michael J. Ford and Gary J. Van BerkelA New Tandem-in-Time and –in-Space Mass Spectrometer for High-Throughput MS/MS.
D.E. Goeringer, A.R. Warren, M.B. Wise, K.J. HartInvestigation of Reserpine Oxidation Using On-Line Electrochemistry/Electrospray Mass Spectrometry.
Vilmos Kertesz and Gary J. Van Berkel
2003
Atmospheric Pressure Ionization Techniques.
Tutorial Lecture by Dr. Gary J. Van BerkelSurface Sampling with Electrospray Mass Spectrometry.
Michael J. Ford
A Tale of Roads Less Traveled: Electrochemistry and Surface Sampling Combined with Electrospray.
October 10, 2003 at the Chemistry Department Seminar at the University of New Orleans.
ORNL Disclaimers
ORNL Site Index
ORNL Search
Provided by Oak Ridge National Laboratory;
A facility managed by UT-Battelle, LLC;
For the U.S. Department of Energy.