Expertise
in mouse genetics is provided by highly trained research staff
and technicians, many with decades of experience in all phases
of experimental design, mutagenesis, transgenesis, phenotyping,
cryopreservation of embryos and germ cells, and data management.
The mouse program is also part of an integrated and multidisciplinary
functional-genomics team working towards discovering genes and
the functions of genes in the mouse genome. The investigators
also pursue specific areas of interest using mouse models (http://bio.lsd.ornl.gov/mgg/).
MGRF team members have a wide range of computational and analytical
expertise that can be brought to bear on questions of nucleic
acid and protein structure and function, biochemical pathway
analysis, gene mapping and cloning using genetic and molecular
techniques, and the tailoring of mouse mutations to specific needs. |