Carmen Mercadal Foster
Carmen M Foster is an Associate Staff Member in the Biosciences Division at ORNL. She received her BS in Biology at the College of Charleston and her MS in Microbiology at the University of Tennessee. She has worked in the Mammalian Genetics Group, creating transgenic and knock-out mice for genes regulating several cancer and disease processes as well as working on the gut microbiome project with Mircea Podar's group. She joined the Biological and Nanoscale Systems Group in 2011 where she is currently the project manager for the Plant-Microbe Interfaces Scientific Focus Area. She is also involved in studying the chemotactic responses of the different microbes that colonize plant roots.
- Campbell JH, Foster CM, Vishnivetskaya T, Campbell AG, Yang ZK, Wymore A, Palumbo AV, Chesler EJ and Podar M. 2012. Host genetic and environmental effects on mouse intestinal microbiota. ISME Journal (2012) 1-12; doi: 10.1038/ismej.2012.54
- Michaud EJ, Culiat CT, Klebig, ML, Barker PE, Cain KT, Carpener DJ, Easter LL, Foster CM, Gardner AW, Guo ZY, Houser KJ, Hughes LA, Kerley MK, Olszewski RE, Pinn I, Shaw DG, Shinpock SG, Wymore AM, Rinchik EM and Johnson DK. 2005. Efficient gene-driven germ-line point mutagenesis of C57Bl/6 mice. BMC Genomics 21; 6:164.
- Khrebtukova, I, Michaud EJ, Foster CM, Stark KL, Garfinkel DJ, and Woychik RP. 1998. Utilization of microhomologous recombination in yeast to generate targeting constructs for mammalian genes. Mutation Research 401: 11-25.
- William G. Richards, Bradley K. Yoder, Robert J. Isfort, Philippe G. Detilleux, Carmen Foster, Nancy Neilsen, Richard P. Woychik and J. Erby Wilkinson. 1996. Oval cell proliferation associated with the murine insertional mutation TgN737Rpw. American Journal of Pathology 149 6: 1919-30.
- T.A. Banks, F.J. Jenkins, S. Kanangat, S. Nair, S. DasGupta, C. M. Foster, and B. T. Rouse. 1994. Vaccination with the immediate-early protein ICP47 of herpes simplex virus-type 1 (HSV1) induces virus-specific lymphoprolifeation, buts fails to protect against lethal challenge. Virology 200(1): 236-45.
- C.M. Mercadal, D. Bouley, D. DeStephano, and B.T. Rouse. 1993. Herpetic Stromal Keratitis in the Reconstituted scid Mouse Model. Journal of Virology 67: 3404-3408.
- S. Martin, C.M. Mercadal, J.P. Wier, and B.T. Rouse. 1992. The Proportion of Herpes Simplex Virus Specific Cytotoxic T Lymphocytes (Tc) That Recognize Glycoprotein C Varies Between Individual Mice and is Dependent Upon the Form of Immunization. Viral Immunology 6: 21-33.
- C.M. Mercadal, M. Slaoui, S.M. Brown, and B.T. Rouse. 1992. Efficacy of Herpes Simplex Virus Type 1 and 2 Mutants to Confer Protection Against Zosteriform Spread in Mice. Viral Immunology 6: 35-42.
- L.A. Coker, C.M. Mercadal, B.T. Rouse and R.N. Moore. 1992. Differential Effects of CD4+ and CD8+ Cells in Acute, Systemic Murine Candidosis. Journal of Leukocyte Biology 51: 305-306.
- M.Z. Doymaz, C.M. Mercadal, D. DeStephano, and B.T. Rouse. 1991. MHC-II Restricted, CD4+ Cytotoxic T Lymphocytes (CTL) Specific for Herpes Simplex Virus-1: Implications for the Development of Herpetic Stromal Keratitis (HSK) in Mice. Clinical Immunology and Immunopathology 6: 98- 409.
- C.M. Mercadal, S. Martin, and B.T. Rouse. 1991. The Apparent Requirement for CD4+ T Cells in Primary Anti-Herpes Simplex Virus Cytotoxic T Lymphocyte Induction Can Be Overcome by Optimal Antigen Presentation. Viral Immunology 4: 177-186.
- E.A. Allen, J.P. Weir, S. Martin, C.M. Mercadal, and B.T. Rouse. 1990. Role of Coexpression of IL-2 and Herpes Simplex Virus Proteins in Recombinant Vaccinia Virus Vectors on Levels of Induced Immunity. Viral Immunology 3: 207-215.
- C.K. Newell, S. Martin, D. Sendele, C.M. Mercadal, and B.T. Rouse. 1989. Herpes Simplex Virus-Induced Stromal Keratitis: Role of T-Lymphocyte Subsets in Immunopathology. Journal of Virology 63: 769-775.
Awards and Recognitions:
- 2002 – Excellence in Science and Technology
- 2004 – Excellence in Science and Technology
- 2011 – Distinguished Achievement Award
Recognized for exceptional laboratory management and exemplary research support to Dr. Ed Michaud and the Functional Genomics Group
Received Award for developing and optimizing the Cryopreserved Mutant Mouse Bank (CMMB) and establishing the Intracytoplasmic sperm injection technique at ORNL for the recovery of mutant mice from Cryopreserved sperm.
In recognition for outstanding administrative support for the Plant-Microbe Interfaces SFA.