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The molybdenum compound resists corrosion in the presence of air and holds its shape at temperatures of 1600ºC. “It may sound simple, but it’s so drastic,” Akinc said. “You’re getting into a temperature regime where the material becomes almost white-hot.” The project, which began in late 1996, divides $300,000 per year among the eight participating DOE national laboratories—Ames, Argonne, INEEL, Lawrence Berkeley, Lawrence Livermore, Los Alamos, Oak Ridge and Sandia—and the University of Illinois. The funding helps redirect research efforts toward Akinc’s material and stimulates collaborative efforts among the 25 scientists involved in the project. There are some kinks in the material that need to be worked out in order to make it a viable alternative to steel and superalloys. Each of the labs is tackling different parts of the problem and sharing the findings with the group. “We’re making significant progress in a relatively short amount of time,” said Oak Ridge’s Roddie Judkins, one of the project’s two coordinators. “We’ve got a lot of good science in this
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Splitting the year between the two research institutions, Mirzabekov is at the center of a joint project that will result in rapid advances in medicine, health care and agriculture, under a new partnership with Motorola Inc. and Packard Instrument Company. The project, which aims at commercializing and marketing advanced biochips and related analytical technologies, is expected to make the process of decoding genes a thousand times faster than with current technologies. “Instead of reading DNA one letter or word at a time, they read whole phrases and sentences at a time,” Mirzabekov said. “It’s like speed-reading the genetic code with one hundred percent comprehension. By combining biochips with robots and computers, we can find one genetic variation among three billion DNA bases in a matter of minutes. Conventional methods take days.” This biotechnology will have myriad applications in life science, including medical diagnostics, drug discovery, environmental restoration and agriculture. Medical diagnostics is where the greatest impact is expected. Widespread use of biochips will remove the guesswork from early treatment of many diseases and conditions. By using less than a drop of test solution, doctors will be able to predict drug efficacy, to diagnose drug resistance to treatment for diseases, and to make on-the-spot identification of specific bacteria, viruses, and other micro-organisms. This makes Mirzabekov the grandfather very happy. “My grandson, by the time he is grown, will be able to carry with him his entire genetic code on a biochip,” he predicts. Submitted by Argonne National Laboratory |