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Research
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David Dahl’s influence stretches to the far reaches of the solar system. Three instruments now hurtling toward Saturn aboard the spacecraft Cassini will analyze cosmic dust and the atmosphere of Titan, Saturn’s largest moon. Dahl’s award-winning ion motion simulation program, SIMION for the PC, helped design the instruments. Here on Earth, machines designed in part by SIMION analyze environmental contaminants, decode DNA, and test urine for illegal drugs. Moreover, SIMION has been used to analyze components used in semiconductor manufacturing, indirectly improving the very computers it runs on. “It’s kind of pervasive,” said Dahl, a LMITCO consulting engineer/scientist in the Chemical and Biological Sciences Department of DOE's Idaho National Engineering and Environmental Laboratory.
Users say SIMION’s beauty lies in its intuitiveness. The program makes ions coursing through electromagnetic fields as easy to visualize as golf balls rolling across a putting green. The simulated ions mimic real ions inside a mass spectrometer. Mystery ions, whether in cosmic dust, environmental contaminant samples, or a drug user’s bodily fluids, can be identified by mass spectrometers based on how the particles move through the machine. Dahl likes to think of SIMION as an “enabling
technology.” Because the program is so user-friendly and intuitive, people
can design instruments creatively and explore options they may not have
conceived of without SIMION’s help. “This represents exactly the kind of
thing a national lab ought to be doing,” he said, “producing, developing
and vigorously proliferating technology so that the maximum number of people
will benefit from the taxpayer’s investment.”
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In 1992, as a new staff member at Pacific Northwest, Campbell began applying what she learned about calcification. She developed Surface Induced Mineralization, a method of depositing a calcium phosphate coating on the surfaces of implants. This coating stimulates growth of new bone cells, therefore grasping the implant more solidly and increasing its longevity. This technology could ease the pain of hip implant patients who must return for a new implant after just 10 years. “As baby boomers grow older, more and more people will need implants,” Campbell said. “And they won’t want to keep going back for more reconstruction.” “It’s our hope that we can help create an implant that only needs to be inserted once,” she adds. “Not only could it reduce the pain and suffering for people, this process could relieve the strain on the health care system.” DOE’s Office of Basic Energy Science funded the research. The project has served as a foundation for similar studies in how this bioactive coating could be used in dental implants and for bone reconstruction. Campbell leads Pacific Northwest’s efforts in its Biomaterials Science and Engineering Laboratory. “Our work is rewarding because it has the
potential to directly affect the quality of a person’s life,” she said.
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